Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, South Korea.
Department of Radiology, GangNeung Asan Hospital, Gangneung, South Korea.
Head Neck. 2019 Apr;41(4):967-973. doi: 10.1002/hed.25530. Epub 2019 Feb 10.
To retrospectively evaluate the false negative rate of ultrasound-guided fine needle aspiration (FNA) according to the nodule size and ultrasound pattern.
We included 432 consecutive thyroid nodules from 384 patients who underwent ultrasound-guided FNA with benign results (≥1 cm). The false negative rate in the nodules was assessed according to the nodule size and ultrasound pattern based on the Korean-Thyroid Imaging Reporting and Data System (K-TIRADS).
The overall false negative rate was 3.2%. There was a trend toward an increasing false negative rate as the K-TIRADS score increased (P < .001). In low or high suspicion nodules (K-TIRADS 3 and 5), there was no significant difference in false negative rate according to the nodule size; however, among the intermediate suspicion nodules (K-TIRADS 4), the false negative rate was higher in large nodules (≥3 cm, P = .039).
The impact of nodule size on the false negative rate differed according to the ultrasound pattern.
本研究旨在回顾性评估根据结节大小和超声模式，超声引导细针抽吸（FNA）的假阴性率。
我们纳入了 384 例患者的 432 个连续甲状腺结节，这些患者均接受了超声引导 FNA 检查且结果为良性（≥1 cm）。根据韩国甲状腺影像报告和数据系统（K-TIRADS），基于结节大小和超声模式评估了结节的假阴性率。
总的假阴性率为 3.2%。随着 K-TIRADS 评分的增加，假阴性率呈上升趋势（P<.001）。在低度或高度可疑结节（K-TIRADS 3 和 5）中，根据结节大小，假阴性率没有显著差异；然而，在中度可疑结节（K-TIRADS 4）中，大结节（≥3 cm，P=.039）的假阴性率更高。
结节大小对假阴性率的影响因超声模式而异。
