Poverennyĭ A M, Semina O V, Semenets T N, Iarilin A A
Biull Eksp Biol Med. 1978 Jun;85(6):708-9.
It was shown that treatment of the bone marrow with the serum reacting with the theta-antigen, irrespective of the presence of the complement, sharply decreases the capacity of its cells to form splenic colonies. Administration of the thymus cells together with the bone marrow to the recipient largely elminates the effect of this system, significantly increasing the splenic colony formation. It is supposed that the antiserum in the bone marrow inactivates the population of cells necessary for the formation of the colonies in the spleen, but differing from the pluripotent stem cells, possibly the population of T-cells.
结果表明,用与θ抗原反应的血清处理骨髓,无论补体是否存在,都会显著降低其细胞形成脾集落的能力。将胸腺细胞与骨髓一起给予受体,在很大程度上消除了该系统的影响,显著增加了脾集落的形成。据推测,骨髓中的抗血清使脾中形成集落所需的细胞群体失活,但不同于多能干细胞,可能是T细胞群体。