Zorina T E, Fomichev A Iu, Cherenkevich S N
Mikrobiologiia. 1988 Nov-Dec;57(6):1007-10.
The goal of the work was to study the sensitivity of isogenic Escherichia coli cells differing in their ability to mediate DNA repair steps to the action of visible light sensitized by chlorine e6. Cells incapable of excision repair as well as those deficient in post-replicative recombination DNA repair were found to be much more sensitive to the combined action of visible light and chlorine e6 as compared to cells whose genes responsible for DNA repair were not damaged. The results indicate that visible light damages bacterial DNA in the presence of chlorine e6.
这项工作的目标是研究在介导DNA修复步骤能力上存在差异的同基因大肠杆菌细胞对由氯e6敏化的可见光作用的敏感性。与负责DNA修复的基因未受损的细胞相比，无法进行切除修复的细胞以及在复制后重组DNA修复方面存在缺陷的细胞对可见光和氯e6的联合作用更为敏感。结果表明，在氯e6存在的情况下，可见光会损伤细菌DNA。
