Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, United States.
Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, United States.
Ocul Surf. 2019 Apr;17(2):336-340. doi: 10.1016/j.jtos.2019.01.010. Epub 2019 Feb 8.
Glaucoma is the leading cause of vision loss in eyes with Boston Keratoprosthesis (KPro). Glaucoma drainage devices (GDDs) have been shown to be effective in controlling glaucoma with KPro. Cicatricial conjunctival disease with forniceal shortening is a major challenge and limitation to the use of GDD. In our series, we report the success of fornix reconstruction in cicatricial ocular surface disease as a staged procedure prior to a combined KPro/GDD surgery.
Retrospective case series involving 4 eyes with surface cicatricization. Three patients with chemical burns and one patient with Ectrodactyly Ectodermal Dysplasia-Clefting syndrome. Preoperative data, surgical interventions, and clinical outcomes were reviewed.
This series represents the first report of fornix reconstruction for combined KPro/GDD surgery. Fornix reconstruction with the aid of AMT with or without OMM grafting is a relatively safe and effective way to manage complex cicatricial surface disease associated with corneal scarring and glaucoma, allowing for subsequent successful implantation of GDD and KPro in cases that were otherwise poor surgical candidates.
青光眼是波士顿角膜(KPro)眼视力丧失的主要原因。已证实青光眼引流装置(GDD)可有效控制 KPro 相关青光眼。穹窿缩短的瘢痕性结结膜疾病是使用 GDD 的主要挑战和限制。在我们的系列研究中,我们报告了在联合 KPro/GDD 手术前,分阶段行穹窿重建术治疗瘢痕性眼表疾病的成功经验。
回顾性病例系列研究,共涉及 4 只眼的表面瘢痕化。3 例化学烧伤患者和 1 例外胚层发育不良-唇腭裂综合征患者。回顾了术前数据、手术干预和临床结果。
这一系列研究代表了首例为联合 KPro/GDD 手术而行穹窿重建的报告。在 AMT 辅助下进行或不进行 OMM 移植的穹窿重建术,是一种相对安全有效的方法,可用于治疗与角膜瘢痕和青光眼相关的复杂瘢痕性表面疾病,为随后在原本手术效果不佳的情况下成功植入 GDD 和 KPro 提供了可能。