Gurley Kiersten L, Edlow Jonathan A
Deparment of Emergency Medicine, Harvard Medical School, Boston, Massachusetts.
Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Semin Neurol. 2019 Feb;39(1):27-40. doi: 10.1055/s-0038-1676857. Epub 2019 Feb 11.
Dizziness is a common chief complaint with an extensive differential diagnosis that includes both benign and serious conditions. Physicians must distinguish the majority of patients who suffer from self-limiting conditions from those with serious illnesses that require acute treatment. The preferred approach to the diagnosis of an acutely dizzy patient emphasizes different aspects of the history to guide a focused physical examination, with the goal of differentiating benign peripheral vestibular conditions from dangerous posterior circulation strokes. Currently, misdiagnoses are frequent and diagnostic testing costs are high. This partly relates to use of an outdated diagnostic paradigm. This commonly used traditional approach relies on dizziness "symptom quality" or "type" (vertigo, presyncope, disequilibrium) to guide inquiry. It does not distinguish benign from dangerous causes and is inconsistent with current best evidence. A better approach categorizes patients into three groups based on timing and triggers. Each category has its own differential diagnosis and targeted bedside approach: (1) acute vestibular syndrome, where bedside physical examination differentiates vestibular neuritis from stroke; (2) spontaneous episodic vestibular syndrome, where associated symptoms help differentiate vestibular migraine from transient ischemic attack; and (3) triggered episodic vestibular syndrome, where the Dix-Hallpike and supine roll test help differentiate benign paroxysmal positional vertigo from posterior fossa structural lesions. The "timing and triggers" diagnostic approach for the acutely dizzy derives from current best evidence and offers the potential to reduce misdiagnosis while simultaneously decreasing diagnostic test overuse, unnecessary hospitalization, and incorrect treatments.
头晕是一种常见的主要症状,其鉴别诊断范围广泛,包括良性和严重疾病。医生必须将大多数患有自限性疾病的患者与需要紧急治疗的严重疾病患者区分开来。对于急性头晕患者的首选诊断方法强调病史的不同方面,以指导有针对性的体格检查,目的是将良性外周前庭疾病与危险的后循环卒中区分开来。目前,误诊很常见,诊断测试成本很高。这部分与使用过时的诊断范式有关。这种常用的传统方法依靠头晕的“症状性质”或“类型”(眩晕、晕厥前状态、平衡失调)来指导问诊。它无法区分良性和危险病因,也与当前的最佳证据不一致。一种更好的方法是根据发作时间和诱发因素将患者分为三组。每组都有其自己的鉴别诊断和有针对性的床边检查方法:(1)急性前庭综合征,床边体格检查可将前庭神经炎与卒中区分开来;(2)自发性发作性前庭综合征,相关症状有助于将前庭性偏头痛与短暂性脑缺血发作区分开来;(3)诱发性发作性前庭综合征,Dix-Hallpike试验和仰卧翻身试验有助于将良性阵发性位置性眩晕与后颅窝结构性病变区分开来。急性头晕的“发作时间和诱发因素”诊断方法源自当前的最佳证据,有可能减少误诊,同时减少诊断测试的过度使用、不必要的住院治疗和错误治疗。