Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Feb 6;53(2):146-152. doi: 10.3760/cma.j.issn.0253-9624.2019.02.005.
Meningococcal meningitis is an acute, severe respiratory infectious disease caused by Neisseria meningitidis. Immunization with meningococcal vaccine is the most effective measure to control and prevent transmission of meningococcal meningitis. Meningococcal vaccines in the Chinese market include meningococcal polysaccharide vaccine, meningococcal polysaccharide conjugate vaccine, and a combined vaccine containing meningococcal polysaccharide conjugate vaccine. This article reviews research progress on the efficacy, safety, and cost-effectiveness of meningococcal vaccines, particularly in the Chinese market, to support appropriate use of the various meningococcal vaccines for preventing meningococcal meningitis.
脑膜炎球菌性脑膜炎是由脑膜炎奈瑟菌引起的一种急性、严重的呼吸道传染病。接种脑膜炎球菌疫苗是控制和预防脑膜炎球菌性脑膜炎传播的最有效措施。中国市场上的脑膜炎球菌疫苗包括脑膜炎球菌多糖疫苗、脑膜炎球菌多糖结合疫苗以及一种含有脑膜炎球菌多糖结合疫苗的联合疫苗。本文综述了脑膜炎球菌疫苗在疗效、安全性和成本效益方面的研究进展，特别是在中国市场的情况，以支持合理使用各种脑膜炎球菌疫苗来预防脑膜炎球菌性脑膜炎。
