Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Department of General Medical Practice, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
J Intensive Care Med. 2020 Dec;35(12):1439-1446. doi: 10.1177/0885066619828338. Epub 2019 Feb 11.
We previously showed that a "10-hour daytime on-site" and "nighttime (NT) on-call" staffing strategy was associated with higher mortality for intensive care unit (ICU) patients admitted during NT than it was for patients admitted during office hours (OH). In here, we evaluated the clinical effects of a 24-hour intensivist staffing model.
We formed an intervention group of 3034 consecutive ICU patients hospitalized from January 2013 to December 2015, and a control group of 2891 patients from our previous study (2009-2011). We applied propensity score matching (PSM) for whole and subgroup analyses adjusting for confounding factors. We compared clinical outcomes of patients under the 2 staffing models using multivariate logistic regression and survival analyses.
After PSM, we balanced the clinical data between the complete cohorts and the subgroups. Comparison of ICU survivals between the intervention and control cohorts yielded no significant differences. However, the intervention was significantly associated with a higher ICU survival in the NT (5:30 pm-07:30 am) admission patients ( = .049) than in those admitted during OH (07:30 am to 5:30 pm; = .456). Additionally, the intervention shortened the LOS ( = .001) and/or LOS ( < .001), reduced the hospital ( = .672) and/or ICU ( = .004) expenses, and resulted in earlier mechanical ventilation extubation ( = .442) as compared to the same variables in the control group, especially for NT admissions.
The 24-hour intensivists staffing could significantly improve ICU outcomes, especially for NT-admission patients in high-acuity, high-volume ICUs with frequent NT admissions.
我们之前的研究表明,与白天(办公时间)在病房的患者相比,夜间(NT)在病房的“10 小时白天在病房和夜间(NT)随叫随到”工作人员配备策略与 ICU 患者的死亡率更高相关。在这里,我们评估了 24 小时主治医生配备模式的临床效果。
我们将 2013 年 1 月至 2015 年 12 月期间住院的 3034 例连续 ICU 患者组成干预组,将我们之前研究(2009-2011 年)中的 2891 例患者组成对照组。我们应用倾向评分匹配(PSM)对全组和亚组进行分析,以调整混杂因素。我们使用多变量逻辑回归和生存分析比较了两种工作人员配备模型下患者的临床结果。
PSM 后,我们平衡了完整队列和亚组的临床数据。干预组和对照组 ICU 存活率的比较没有显著差异。然而,干预组与 NT(下午 5:30 至上午 7:30)入院患者的 ICU 存活率显著相关(=0.049),而与 OH(上午 7:30 至下午 5:30)入院患者的 ICU 存活率无显著相关(=0.456)。此外,与对照组相比,干预组缩短了 LOS(=0.001)和/或 LOS(<0.001),降低了医院(=0.672)和/或 ICU(=0.004)费用,并使机械通气拔管更早(=0.442),尤其是 NT 入院患者。
24 小时主治医生配备可以显著改善 ICU 结果,特别是对于高风险、高容量 ICU 中频繁 NT 入院的 NT 入院患者。