Bull World Health Organ. 1978;56(2):229-40.
Recent progress in the production of interferons and in knowledge of their mode of action has opened new possibilities for their prophylactic or therapeutic use, for example, in the treatment of influenza. Such use still needs further evaluation as do the presently available chemical antiviral drugs. The activity of interferon against other viral infections is also promising and preliminary trials on their effect on certain tumours have begun at a number of centres. There is, however, a need for quality control of interferon preparations and recommendations for the production and use of interferon as well as for further research are included in this Memorandum.
干扰素生产方面的最新进展以及对其作用方式的了解为其预防性或治疗性应用开辟了新的可能性,例如用于治疗流感。与目前可用的化学抗病毒药物一样,这种应用仍需要进一步评估。干扰素对其他病毒感染的活性也很有前景,一些中心已经开始了关于其对某些肿瘤影响的初步试验。然而,需要对干扰素制剂进行质量控制,本备忘录中包含了关于干扰素生产和使用的建议以及进一步研究的内容。