Chu K Y
Bull World Health Organ. 1978;56(2):313-22.
Urinary schistosomiasis is highly prevalent along the shores of the Volta Lake in Ghana, where transmission occurs focally in man-water contact sites. The intermediate host, Bulinus truncatus rohlfsi, prefers to harbour in Ceratophyllum, a common aquatic weed in the lake. Removal of this weed reduced the density of both infected and uninfected snails, but not sufficiently to interrupt transmission.Niclosamide was applied at 1, 0.7, and 0.5 mg/l in combination with weed removal at five water contact sites in December, January, and February, respectively. Plastic sheets were used to isolate treated sites from the main body of the lake. Snail surveys were carried out at short intervals to assess the effectiveness of these intervention measures. Niclosamide at 0.5 mg/l applied after weed removal was effective in killing the snails. The overall results indicate that snail control along the entire lake shore is impossible but that focal control of cercarial transmission at water contact sites is attainable and shows promise.
在加纳沃尔特湖沿岸，泌尿血吸虫病高度流行，其传播集中在人与水接触的地点。中间宿主罗氏截口圆扁螺更喜欢栖息在湖中常见的水草金鱼藻中。清除这种水草降低了受感染和未受感染蜗牛的密度，但不足以阻断传播。分别于12月、1月和2月，在五个水接触点以1毫克/升、0.7毫克/升和0.5毫克/升的浓度施用氯硝柳胺，并结合清除水草。使用塑料布将处理过的地点与湖泊主体隔离开来。每隔一段时间进行蜗牛调查，以评估这些干预措施的效果。清除水草后以0.5毫克/升的浓度施用氯硝柳胺可有效杀死蜗牛。总体结果表明，对整个湖岸进行蜗牛控制是不可能的，但在水接触点对尾蚴传播进行局部控制是可行的，且显示出前景。
