急性痘疮样苔藓样糠疹的临床特征与治疗：一项越南回顾性研究
Clinical Aspects and Treatment of Pityriasis Lichenoides Et Varioliformis Acuta: A Retrospective Vietnamese Study.
作者信息
Van Thuong Nguyen, Thi Tuyen Nguyen, Huu Doanh Le, Huu Nghi Dinh, Thi Mai Le, Minh Thu Nguyen, Huyen My Le, Gandolfi Marco, Satolli Francesca, Feliciani Claudio, Tirant Michael, Vojvodic Aleksandra, Lotti Torello
机构信息
National Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Dermatology and Venereology Faculty, Hanoi Medical University, Hanoi, Vietnam.
出版信息
Open Access Maced J Med Sci. 2019 Jan 23;7(2):198-199. doi: 10.3889/oamjms.2019.005. eCollection 2019 Jan 30.
BACKGROUND
Pityriasis lichenoides et varioliformis acuta (PLEVA) is an uncommon condition which presents acutely with papulo-vesicles that may develop necrotic, ulcerative, or hemorrhagic changes.
AIM
We studied clinical, and treatment characteristics of PLEVA hospitalised patients at our hospital from September 2009 to December 2014.
METHODS
The records of 15 PLEVA patients were retrospectively reviewed.
RESULTS
The median age of onset was 21.8 ± 18.81 (from 1 to 68), male to female ratio was 2/1. The common area of onset was trunk (60.0%) and extremities (33.3%). Clinical features were purpuric papules (100%), hemorrhagic crusted papules (46.7%), pustular purpuric papules (40%), and necrotic ulcerating lesions (13.3%).
CONCLUSION
All patients were received systemic antibiotics (macrolides: 53.3%, others: 46.7%), 2 patients were added immunosuppressive drugs. A 1-year-old patient died, others had a good response.
背景
急性痘疮样苔藓样糠疹（PLEVA）是一种罕见疾病，急性起病，表现为丘疹水疱，可出现坏死、溃疡或出血性改变。
目的
我们研究了2009年9月至2014年12月在我院住院的PLEVA患者的临床及治疗特征。
方法
回顾性分析15例PLEVA患者的病历。
结果
发病年龄中位数为21.8±18.81岁（1至68岁），男女比例为2/1。常见发病部位为躯干（60.0%）和四肢（33.3%）。临床特征为紫癜性丘疹（100%）、出血性结痂丘疹（46.7%）、脓疱性紫癜性丘疹（40%）和坏死溃疡性病变（13.3%）。
结论
所有患者均接受了全身抗生素治疗（大环内酯类：53.3%，其他：46.7%），2例患者加用了免疫抑制药物。1例1岁患者死亡，其他患者反应良好。
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