口服伊曲康唑治疗越南成年患者脂溢性皮炎的疗效
Efficacy of Oral Itraconazole in the Treatment of Seborrheic Dermatitis in Vietnamese Adults Patients.
作者信息
Van Thuong Nguyen, Thi Ngo Hoang, Van Tam Hoang, Van Hung Le, Huu Nghi Dinh, Minh Phuong Pham Thi, Cam Van Tran, Huyen My Le, Hau Khang Tran, Gandolfi Marco, Satolli Francesca, Feliciani Claudio, Tirant Michael, Vojvodic Aleksandra, Lotti Torello
机构信息
National Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Dermatology and Venerology Faculty, Hanoi Medical University, Hanoi, Vietnam.
出版信息
Open Access Maced J Med Sci. 2019 Jan 20;7(2):224-226. doi: 10.3889/oamjms.2019.056. eCollection 2019 Jan 30.
AIM
This longitudinal study aims to evaluate the efficacy of oral itraconazole in the treatment of seborrheic dermatitis in Vietnamese patients.
METHODS
Thirty patients were enrolled at National Hospital of Dermatology and Venereology, Hanoi, Vietnam and were treated with oral itraconazole (200 mg daily in 14 days followed by 200 mg weekly in 4 weeks). The clinical severity was assessed by a four-parameter scoring system. All patients completed the six-week regimen with good adherence.
RESULTS
At the week 2nd, 70% of the patients had moderate to severe diseases. At the week 6th, 63.4% of the patients achieve clearance of the lesions, and none had severe disease. No side effects were reported.
CONCLUSION
Oral itraconazole can be an option for seborrheic dermatitis because of good efficacy, safety profile and adherence.
目的
本纵向研究旨在评估口服伊曲康唑治疗越南患者脂溢性皮炎的疗效。
方法
30名患者入选越南河内国家皮肤科和性病医院，接受口服伊曲康唑治疗（14天内每日200毫克，随后4周内每周200毫克）。临床严重程度通过四参数评分系统进行评估。所有患者均以良好的依从性完成了六周疗程。
结果
在第2周时，70%的患者患有中度至重度疾病。在第6周时，63.4%的患者皮损消退，且无一例患有严重疾病。未报告有副作用。
结论
由于疗效良好、安全性高且依从性好，口服伊曲康唑可作为脂溢性皮炎的一种治疗选择。
Zotero 插件