Xuan Tam Huynh Thi, Thi Van Bui, Ngoc Anh Tran, Van Em Dang, Dang Quyet Tran, Van Thuong Nguyen, Minh Phuong Pham Thi, Thi Lan Pham, Huu Nghi Dinh, Gandolfi Marco, Satolli Francesca, Feliciani Claudio, Tirant Michael, Vojvodic Aleksandra, Lotti Torello
Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.
108 Institute of Clinical Medical and Pharmaceutical Sciences, Hanoi, Vietnam.
Open Access Maced J Med Sci. 2019 Jan 27;7(2):302-303. doi: 10.3889/oamjms.2019.066. eCollection 2019 Jan 30.
A cross-sectional study was performed on 48 psoriasis Vietnamese patients treated with metformin as an add-on for methotrexate and 48 psoriasis patients treated methotrexate alone. The mean PASI scores were 5.25 ± 5.72. Total QOL scores had a slight difference between patients treated metformin combined with methotrexate and methotrexate alone (62.32 ± 18.1 vs 60.91 ± 19.63). Combined therapy with metformin and methotrexate contributes to significantly improve the quality of life for patients with psoriasis.
对48例接受二甲双胍联合甲氨蝶呤治疗的越南银屑病患者和48例仅接受甲氨蝶呤治疗的银屑病患者进行了一项横断面研究。平均PASI评分为5.25±5.72。在接受二甲双胍联合甲氨蝶呤治疗的患者和仅接受甲氨蝶呤治疗的患者之间,总生活质量评分存在轻微差异(62.32±18.1对60.91±19.63)。二甲双胍和甲氨蝶呤联合治疗有助于显著改善银屑病患者的生活质量。