• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新型口服抗凝剂治疗椎动脉夹层:病例报告

Novel Oral Anticoagulants as Treatment for Vertebral Artery Dissection: Case Report.

作者信息

Góngora-Rivera Fernando, Martínez Héctor R, Cantu-Martinez Leonel, Camara-Lemarroy Carlos R, Moreno-Andrade Talía

机构信息

Servicio de Neurología del Hospital Universitario Dr. José Eleuterio González de la Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.

Instituto de Neurologia y Neurocirugia, Facultad de Medicina y Ciencias de la Salud, Instituto Tecnologico de Monterrey, Nuevo León, México.

出版信息

J Vasc Interv Neurol. 2018 Nov;10(2):56-58.

PMID:30746012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6350868/
Abstract

BACKGROUND AND PURPOSE

Cervical artery dissections, which may be traumatic or spontaneous, account for a significant proportion of strokes in the young. Antithrombotic therapy is the mainstay of treatment, but new oral anticoagulants could be an alternative treatment to the optimal strategy of anticoagulation followed by antiplatelet drugs.

SUMMARY OF CASE

We report the case of a 40-year-old patient with a spontaneous vertebral artery dissection who developed a cerebellar ischemic stroke, who had a favorable outcome and complete vessel recanalization after three months of treatment with the oral factor Xa inhibitor rivaroxaban.

CONCLUSION

New oral anticoagulant could constitute an alternative and new therapeutic option in cervical artery dissections.

摘要

背景与目的

颈动脉瘤夹层形成,可能是外伤性或自发性的,在年轻人中风中占相当大的比例。抗血栓治疗是主要的治疗方法,但新型口服抗凝剂可能是抗凝治疗后使用抗血小板药物这一最佳策略的替代治疗方法。

病例摘要

我们报告一例40岁自发性椎动脉夹层形成患者,该患者发生了小脑缺血性中风,经口服Xa因子抑制剂利伐沙班治疗三个月后,取得了良好的疗效,血管完全再通。

结论

新型口服抗凝剂可能成为颈动脉瘤夹层形成的一种替代且新的治疗选择。

相似文献

1
Novel Oral Anticoagulants as Treatment for Vertebral Artery Dissection: Case Report.新型口服抗凝剂治疗椎动脉夹层:病例报告
J Vasc Interv Neurol. 2018 Nov;10(2):56-58.
2
Oral Anticoagulant and Antiplatelet Therapy for Cervical Artery Dissection: A Meta-Analysis of Clinical Trials.口服抗凝和抗血小板治疗颈动脉夹层:临床试验的荟萃分析。
Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211051708. doi: 10.1177/10760296211051708.
3
Rivaroxaban in cervical and "cervico-cerebral" artery dissections: a new therapeutic option?利伐沙班治疗颈内动脉和“颈脑”动脉夹层:一种新的治疗选择?
Neurol Sci. 2019 Aug;40(8):1591-1596. doi: 10.1007/s10072-019-03882-8. Epub 2019 Apr 12.
4
Anticoagulation vs Antiplatelet Treatment in Patients with Carotid and Vertebral Artery Dissection: A Study of 370 Patients and Literature Review.颈动脉和椎动脉夹层患者的抗凝治疗与抗血小板治疗:370例患者的研究及文献综述
Neurosurgery. 2017 Mar 1;80(3):368-379. doi: 10.1093/neuros/nyw086.
5
Efficacy and safety of novel oral anticoagulants in patients with cervical artery dissections.新型口服抗凝剂在颈内动脉夹层患者中的疗效与安全性
Cerebrovasc Dis. 2014;38(4):247-53. doi: 10.1159/000366265. Epub 2014 Nov 13.
6
Extracranial carotid and vertebral artery dissection: a review.颅外颈动脉和椎动脉夹层:综述
Can J Neurol Sci. 2008 May;35(2):146-52. doi: 10.1017/s0317167100008556.
7
Helsinki experience on nonvitamin K oral anticoagulants for treating cervical artery dissection.赫尔辛基使用非维生素K口服抗凝剂治疗颈动脉夹层的经验。
Brain Behav. 2015 Aug;5(8):e00349. doi: 10.1002/brb3.349. Epub 2015 May 30.
8
Early Anticoagulation or Antiplatelet Therapy Is Critical in Craniocervical Artery Dissection: Results from the COMPASS Registry.早期抗凝或抗血小板治疗在颅颈动脉夹层中至关重要:来自 COMPASS 登记处的结果。
Cerebrovasc Dis. 2020;49(4):369-374. doi: 10.1159/000509415. Epub 2020 Jul 30.
9
Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results.抗血小板治疗与抗凝治疗在颈动脉夹层中的应用:中风研究中的颈动脉夹层(CADISS)随机临床试验最终结果。
JAMA Neurol. 2019 Jun 1;76(6):657-664. doi: 10.1001/jamaneurol.2019.0072.
10
Antithrombotic drugs for carotid artery dissection.用于颈动脉夹层的抗血栓药物。
Cochrane Database Syst Rev. 2000(4):CD000255. doi: 10.1002/14651858.CD000255.

引用本文的文献

1
Bilateral Vertebral Artery Dissection: A Case Report with Literature Review.双侧椎动脉夹层:一例病例报告并文献复习
Case Rep Med. 2020 May 25;2020:8180926. doi: 10.1155/2020/8180926. eCollection 2020.

本文引用的文献

1
Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial.抗血小板治疗与抗凝治疗在颈内动脉夹层(CADISS)中的对比:一项随机试验。
Lancet Neurol. 2015 Apr;14(4):361-7. doi: 10.1016/S1474-4422(15)70018-9. Epub 2015 Feb 12.
2
Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.《卒中和短暂性脑缺血发作患者卒中预防指南:美国心脏协会/美国卒中协会医疗保健专业人员指南》。
Stroke. 2014 Jul;45(7):2160-236. doi: 10.1161/STR.0000000000000024. Epub 2014 May 1.
3
Rivaroxaban in acute coronary syndromes--is it prime time?利伐沙班用于急性冠状动脉综合征——时机已到?
Expert Rev Cardiovasc Ther. 2014 Jun;12(6):649-58. doi: 10.1586/14779072.2014.910118. Epub 2014 Apr 19.
4
Rivaroxaban attenuates leukocyte adhesion in the microvasculature and thrombus formation in an experimental mouse model of type 2 diabetes mellitus.利伐沙班可减轻 2 型糖尿病实验小鼠模型中小血管中的白细胞黏附及血栓形成。
Thromb Res. 2014 Feb;133(2):276-80. doi: 10.1016/j.thromres.2013.11.013. Epub 2013 Nov 25.
5
Spontaneous cervical and cerebral arterial dissections: diagnosis and management.自发性颈内动脉和大脑动脉夹层:诊断与治疗。
Neuroimaging Clin N Am. 2013 Nov;23(4):661-71. doi: 10.1016/j.nic.2013.03.013. Epub 2013 May 17.
6
Antiplatelets versus anticoagulants for the treatment of cervical artery dissection: Bayesian meta-analysis.抗血小板药物与抗凝药物治疗颈动脉夹层:贝叶斯荟萃分析。
PLoS One. 2013 Sep 5;8(9):e72697. doi: 10.1371/journal.pone.0072697. eCollection 2013.
7
Current optimal assessment and management of carotid and vertebral spontaneous and traumatic dissection.当前颈动脉和椎动脉自发性和外伤性夹层的最佳评估和管理。
Angiology. 2014 Apr;65(4):274-83. doi: 10.1177/0003319712475154. Epub 2013 Feb 11.
8
Clinical characteristics of symptomatic vertebral artery dissection: a systematic review.症状性椎动脉夹层的临床特征:一项系统评价
Neurologist. 2012 Sep;18(5):245-54. doi: 10.1097/NRL.0b013e31826754e1.
9
Arterial antithrombotic activity of rivaroxaban, an orally active factor Xa inhibitor, in a rat electrolytic carotid artery injury model of thrombosis.利伐沙班(一种口服活性Xa因子抑制剂)在大鼠颈动脉血栓形成电解损伤模型中的动脉抗血栓活性。
Blood Coagul Fibrinolysis. 2011 Dec;22(8):720-6. doi: 10.1097/MBC.0b013e32834cb30e.
10
Cerebrovascular dissections--a review part I: Spontaneous dissections.脑血管夹层——综述部分 I:自发性夹层。
Neurosurgery. 2011 Jan;68(1):242-57; discussion 257. doi: 10.1227/NEU.0b013e3182012323.