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抗血栓治疗中的出血风险:叙述性综述。

The Bleeding Risk in Antithrombotic Therapies: A Narrative Review.

机构信息

Division of Angiology, Heart and Vessel Department, Lausanne University Hospital, Lausanne, Switzerland.

出版信息

Curr Vasc Pharmacol. 2020;18(3):237-248. doi: 10.2174/1570161117666190212112743.

DOI:10.2174/1570161117666190212112743
PMID:30747072
Abstract

Bleeding represents the most important complication of antithrombotic treatment, including anticoagulant and antiplatelet therapies. A number of scores were proposed to evaluate the risk of bleeding both for anticoagulant and antiplatelet treatment. In the last decade, 5 bleeding risk scores were published for use in atrial fibrillation patients, and 3 scores for patients receiving anticoagulants for venous thromboembolism therapy or prophylaxis. In addition, 3 scores were recently developed to assess inhospital or short-term bleeding risk in patients receiving antiplatelet therapy after Acute Coronary Syndrome (ACS) and Percutaneous Coronary Intervention (PCI). Furthermore, 3 additional scores have focused on long-term bleeding in outpatients receiving dual antiplatelet therapy after PCI. The aim of this review is to consider the evidence on bleeding scores.

摘要

出血是抗栓治疗(包括抗凝和抗血小板治疗)最重要的并发症。已经提出了许多评分来评估抗凝和抗血小板治疗的出血风险。在过去的十年中,已经发表了 5 个用于房颤患者的出血风险评分,以及 3 个用于接受抗凝治疗预防或治疗静脉血栓栓塞症的患者的评分。此外,最近还开发了 3 个评分来评估急性冠状动脉综合征(ACS)和经皮冠状动脉介入治疗(PCI)后接受抗血小板治疗的患者的住院或短期出血风险。此外,还有 3 个额外的评分关注的是 PCI 后接受双联抗血小板治疗的门诊患者的长期出血风险。本综述的目的是考虑关于出血评分的证据。

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引用本文的文献

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J Am Heart Assoc. 2019 Sep 17;8(18):e014000. doi: 10.1161/JAHA.119.014000. Epub 2019 Sep 5.