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治疗效果还是有效治疗?与开胸心脏按压和开胸心肺复苏相比,接受主动脉内球囊阻断复苏术的患者心脏压缩分数和呼气末二氧化碳水平更高。

Treatment Effect or Effective Treatment? Cardiac Compression Fraction and End-tidal Carbon Dioxide Are Higher in Patients Resuscitative Endovascular Balloon Occlusion of the Aorta Compared with Resuscitative Thoracotomy and Open-Chest Cardiac Massage.

作者信息

Teeter William A, Bradley Matthew J, Romagnoli Anna, Hu Peter, Li Yao, Stein Deborah M, Scalea Thomas M, Brenner Megan

机构信息

R Adams Cowley Shock Trauma Center, Baltimore, Maryland, USA.

出版信息

Am Surg. 2018 Oct 1;84(10):1691-1695.

PMID:30747696
Abstract

The purpose of this study is to compare end-tidal carbon dioxide (EtCO₂) during resuscitation of open-chest cardiac massage (OCCM) with aortic cross-clamp (ACC) receiving resuscitative endovascular balloon occlusion of the aorta (REBOA) with closed-chest compressions (CCCs). Patients who received REBOA were compared with patients receiving OCCM for traumatic arrest using continuous vital sign monitoring and videography. Thirty-three patients were enrolled in the REBOA group and 18 patients were enrolled in the OCCM group. Of the total patients, 86.3 per cent were male with a mean age of 36.2 ± 13.9 years. Ninety-four percent of patients suffered penetrating trauma in the OCCM group compared with 30.3 per cent of the REBOA group ( = <0.001). Before aortic occlusion (AO), there was no difference in initial EtCO₂ values, but mean, median, peak, and final EtCO₂ values were lower in OCCM ( < 0.005). During CPR after AO, the initial, mean, and median values were higher with REBOA ( = 0.015, 0.036, and 0.038). The rate of return of spontaneous circulation was higher in REBOA OCCM (20/33 [60.1%] 5/18 [33.3%]; = 0.04), and REBOA patients survived to operative intervention more frequently ( = 0.038). REBOA patients had greater total cardiac compression fraction (CCF) before AO than OCCM (85.3 ± 12.7% 35.2 ± 18.6%, < 0.0001) and after AO (88.3 ± 7.8% 71.9 ± 24.4%, = 0.0052). REBOA patients have higher EtCO₂ and cardiac compression fraction before and after AO compared with patients who receive OCCM.

摘要

本研究的目的是比较在接受复苏性血管内主动脉球囊阻断术(REBOA)的开胸心脏按压(OCCM)并进行主动脉交叉钳夹(ACC)与闭胸按压(CCC)复苏期间的呼气末二氧化碳(EtCO₂)情况。通过持续生命体征监测和摄像,将接受REBOA的患者与因创伤性心脏骤停接受OCCM的患者进行比较。REBOA组纳入33例患者,OCCM组纳入18例患者。在所有患者中,86.3%为男性,平均年龄为36.2±13.9岁。OCCM组94%的患者遭受穿透性创伤,而REBOA组为30.3%(P<0.001)。在主动脉阻断(AO)前,初始EtCO₂值无差异,但OCCM组的平均、中位数、峰值和最终EtCO₂值较低(P<0.005)。在AO后的心肺复苏期间,REBOA组的初始、平均和中位数EtCO₂值较高(P分别为0.015、0.036和0.038)。REBOA组自主循环恢复率高于OCCM组(20/33[60.1%]对5/18[33.3%];P=0.04),且REBOA组患者更频繁地存活至手术干预(P=0.038)。REBOA组患者在AO前的总心脏按压分数(CCF)高于OCCM组(85.3±12.7%对35.2±18.6%,P<0.0001),AO后也是如此(88.3±7.8%对71.9±24.4%,P=0.0052)。与接受OCCM的患者相比,REBOA组患者在AO前后的EtCO₂和心脏按压分数更高。

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