Gilutz Harel, Shindel Sevatlana, Shoham-Vardi Ilana
From the Department of Cardiology, Goldman School of Medicine, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beersheba, Israel.
Department of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beersheba, Israel.
Crit Pathw Cardiol. 2019 Mar;18(1):40-46. doi: 10.1097/HPC.0000000000000165.
Adherence to guidelines for the initial treatment of ST-Segment Elevation Myocardial Infarction has been thoroughly studied, whereas the study of emergency department (ED) adherence to guidelines for Non-ST-Segment Elevation Myocardial Infarction-Acute Coronary Syndrome (NSTEMI-ACS) has been much scarcer. The recommended guidelines for the initial prompt workup and treatment of NSTEMI-ACS remains a challenge.
We studied adherence to guidelines for NSTEMI in the ED.
A single-center, retrospective study of consecutive patients with NSTEMI admitted to a tertiary hospital and discharged alive between March 2013 and March 2014. ED records were manually reviewed for adherence to prespecified parameters. Cases with sudden death, shock, or type-II NSTEMI were excluded. Canadian Triage and Acuity Scale score system was used for triage in the ED.
Adherence rates were 33.3%/24.6% of 240 patients for ECG/troponin obtained within 10/60 minutes receptively and 31.3% for anticoagulation within 15 minutes from diagnosis of ACS. Females were less likely to undergo electrocardiography (P = 0.009) or troponin-level tests within the specified timeframe (P = 0.043). Many cardiovascular risk markers were missed. Global Registry of Acute Coronary Events score was not used to risk stratify patients.
Prompt identification and early medical treatment of NSTEMI in the ED is lacking. Better computerized medical history assembly, attention to typical and atypical clinical presentation, and the employment of an appropriate cardiologic risk stratification method may unblind the treating teams at the point of care and improve adherence to NSTEMI guidelines.
ST 段抬高型心肌梗死初始治疗指南的遵循情况已得到充分研究,而急诊科(ED)对非 ST 段抬高型心肌梗死-急性冠状动脉综合征(NSTEMI-ACS)指南的遵循情况研究则少得多。NSTEMI-ACS 初始快速检查和治疗的推荐指南仍然是一项挑战。
我们研究了急诊科对 NSTEMI 指南的遵循情况。
对 2013 年 3 月至 2014 年 3 月期间在一家三级医院住院且存活出院的连续 NSTEMI 患者进行单中心回顾性研究。人工查阅 ED 记录以确定是否符合预先设定的参数。排除猝死、休克或 II 型 NSTEMI 病例。ED 采用加拿大分诊和 acuity 量表评分系统进行分诊。
240 例患者中,分别在 10/60 分钟内进行心电图/肌钙蛋白检查的遵循率为 33.3%/24.6%,从 ACS 诊断起 15 分钟内进行抗凝治疗的遵循率为 31.3%。女性在规定时间内进行心电图检查(P = 0.009)或肌钙蛋白水平检测(P = 0.043)的可能性较小。许多心血管风险标志物被遗漏。未使用急性冠状动脉事件全球注册评分对患者进行风险分层。
急诊科对 NSTEMI 的及时识别和早期药物治疗不足。更好的计算机化病史收集、关注典型和非典型临床表现以及采用适当的心脏风险分层方法可能会使治疗团队在护理点不再盲目,并提高对 NSTEMI 指南的遵循率。