Hare E
Bethlem Royal Hospital.
Br J Psychiatry. 1988 Oct;153:521-31. doi: 10.1192/bjp.153.4.521.
The hypothesis that schizophrenia is a recent disease can explain why descriptions of schizophrenia-like disorders were rare before 1800, why the prevalence of insanity in the Western world increased during the 19th but remained low in the non-Western world until the 20th century, and why schizophrenia has become milder in the West during recent decades. It also explains why schizophrenia has 'persisted' in spite of its associated low fertility. The evidence for the hypothesis is somewhat frail, but perhaps not more so than that for alternative hypotheses.
精神分裂症是一种现代疾病这一假说,可以解释为什么1800年以前关于精神分裂症样障碍的描述很少,为什么19世纪西方世界精神错乱的患病率上升,而直到20世纪非西方世界的患病率一直很低,以及为什么近几十年来西方的精神分裂症症状变得较为轻微。它还解释了为什么尽管精神分裂症与低生育率相关,但仍然“持续存在”。该假说的证据有些薄弱,但也许并不比其他替代假说的证据更薄弱。