Tarrier N, Barrowclough C, Vaughn C, Bamrah J S, Porceddu K, Watts S, Freeman H
Department of Psychology, Salford Health Authority, Prestwich Hospital, Manchester.
Br J Psychiatry. 1988 Oct;153:532-42. doi: 10.1192/bjp.153.4.532.
Schizophrenic patients were recruited into a trial of a prophylactic behavioural intervention with families. Families with at least one high Expressed Emotion (EE) relative were randomly allocated to one of four intervention groups: Behavioural Intervention Enactive; Behavioural Intervention Symbolic; Education Only; Routine Treatment. Patients from low-EE families were randomly allocated to two groups: Education Only or Routine Treatment. Relapse rates over nine months after discharge were significantly lower for patients in the two Behavioural Intervention, compared with Education Only and Routine Treatment groups. There was little difference between the two low-EE groups. Patients returning to high-EE relatives showed significantly higher relapse rates than those returning to low-EE relatives, in groups not receiving active intervention. Changes from high to low EE occurred in the Behavioural Intervention groups, and similar although less extensive changes occurred in the Education Only and Routine Treatment groups. Changes in criticism and marked emotional over-involvement (EOI) occurred generally in high-EE groups but were larger in magnitude in the Enactive and Symbolic groups. Reduction of hostility only occurred in the Behavioural Intervention groups. These results give partial support for the causal role of EE in relapse. There were no significant differences between the groups with respect to contact with the psychiatric services or medication.
精神分裂症患者被招募进一项针对家庭的预防性行为干预试验。至少有一名高情感表达(EE)亲属的家庭被随机分配到四个干预组之一:行为干预(主动式);行为干预(象征性);仅教育;常规治疗。来自低EE家庭的患者被随机分配到两组:仅教育或常规治疗。与仅教育组和常规治疗组相比,两个行为干预组的患者出院后九个月的复发率显著更低。两个低EE组之间差异不大。在未接受积极干预的组中,回到高EE亲属身边的患者复发率显著高于回到低EE亲属身边的患者。行为干预组中出现了从高EE到低EE的变化,仅教育组和常规治疗组也出现了类似但程度较轻的变化。批评和显著的情感过度卷入(EOI)的变化一般发生在高EE组,但在主动式和象征性组中变化幅度更大。敌意的减少仅发生在行为干预组。这些结果部分支持了EE在复发中的因果作用。在与精神科服务机构的接触或用药方面,各小组之间没有显著差异。