Linszen D, Dingemans P, Van der Does J W, Nugter A, Scholte P, Lenior R, Goldstein M J
Academic Medical Centre, University of Amsterdam, Department of Psychiatry, The Netherlands.
Psychol Med. 1996 Mar;26(2):333-42. doi: 10.1017/s0033291700034723.
The effect of in-patient and individual orientated psychosocial intervention (IPI) and in-patient and individual and family orientated intervention (IPFI) across levels of expressed emotion (EE) on relapse was compared in a group of patients with recent onset schizophrenic disorders. Patients were randomly assigned to an individual orientated psychosocial intervention programme or to an identical psychosocial programme plus a behavioural family intervention. Seventy-six patients were studied during a 12 month out-patient treatment period after an in-patient treatment programme in which parents followed a psychoeducational programme. Overall relapse rates during the out-patient interventions were low (16%). Adding family intervention to the psychosocial intervention did not affect the relapse rate. Patients in low EE families relapsed slightly more often during the psychosocial plus family intervention. In-patient treatment with psychoeducation for parents, followed by an out-patient psychosocial intervention programme, has a favourable impact on relapse. Additional family intervention may increase stress in low EE families, thus affecting relapse in their children.
在一组近期发病的精神分裂症患者中，比较了针对不同表达性情绪（EE）水平的住院及个体导向心理社会干预（IPI）和住院及个体与家庭导向干预（IPFI）对复发的影响。患者被随机分配到个体导向心理社会干预项目或相同的心理社会项目加行为家庭干预。在住院治疗项目后，对76名患者进行了为期12个月的门诊治疗期研究，在此期间，患者的父母参加了一个心理教育项目。门诊干预期间的总体复发率较低（16%）。在心理社会干预中增加家庭干预对复发率没有影响。低EE家庭的患者在心理社会加家庭干预期间复发的频率略高。对父母进行住院心理教育治疗，随后进行门诊心理社会干预项目，对复发有积极影响。额外的家庭干预可能会增加低EE家庭的压力，从而影响其子女的复发情况。
