Fekete I
Experientia. 1978 Jul 15;34(7):827-8. doi: 10.1007/BF01939643.
Alloxan treatment induces a decrease of orotic acid content in various organs of carp, frog, pigeon and rat, parallel to a decrease of liver and muscle glycogen content. Loss of orotic acid and glycogen cannot be prevented by orotic acid and carbamyl phosphate given i.p. Mice, rats and pigeons use up and excrete exogenous orotic acid rapidly, but carps and frogs accumulate it.
四氧嘧啶处理会导致鲤鱼、青蛙、鸽子和大鼠各器官中乳清酸含量降低,同时肝脏和肌肉糖原含量也会下降。腹腔注射乳清酸和氨基甲酰磷酸并不能阻止乳清酸和糖原的流失。小鼠、大鼠和鸽子会迅速消耗并排泄外源性乳清酸,但鲤鱼和青蛙会积累它。