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复杂主动脉弓重建术后的新生儿声带运动障碍:诊断后家长应期待什么?

Neonatal vocal fold motion impairment after complex aortic arch reconstruction: What should parents expect after diagnosis?

作者信息

Rodney Jennifer P, Thompson Jess L, Anderson Michael P, Burkhart Harold M

机构信息

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.

出版信息

Int J Pediatr Otorhinolaryngol. 2019 May;120:40-43. doi: 10.1016/j.ijporl.2019.02.006. Epub 2019 Feb 5.

Abstract

OBJECTIVES

To study the incidence, sequelae, follow up, and recovery rate of vocal fold motion impairment (VFMI) after complex aortic arch reconstruction in neonates.

STUDY DESIGN

Retrospective case control study.

METHODS

We retrospectively evaluated 105 neonates who underwent complex aortic arch reconstruction from 2014 to 2016. We compared patients that did have VFMI compared to a control group of patients with normal vocal fold movement. Descriptive statistics were computed for all demographic and clinical variables by treatment group.

RESULTS

36% of patients were evaluated for VFMI (n = 38) by an otolaryngologist. The incidence of VFMI was 22% (n = 23). Females were more likely to have VFMI (p = 0.02). Aspiration was more common in patients with VFMI (p = 0.006). The difference in age, weight, incidence of pneumonia, nasogastric tube, gastrostomy, total length of stay, genetic anomaly, and reintubation was not significant between the VFMI group and control group (p > 0.05). Tracheostomy was not performed in any patients with unilateral paralysis. Only 61% of patients followed up in clinic (n = 14). 64% of patients showed improvement or resolution (n = 9). Average time to improvement was 4.8 months. Average time to complete resolution was 10.5 months.

CONCLUSIONS

VFMI after complex aortic arch reconstruction is relatively common. Despite increased aspiration in patients with VFMI, pneumonia did not occur at all in either group. Tracheostomy was not necessary in any patients with a unilateral paralysis. Most patients showed an improvement in the VFMI within 5 months of surgery. Our data support the need for otolaryngology follow-up after the diagnosis of VFMI.

摘要

目的

研究新生儿复杂主动脉弓重建术后声带运动障碍(VFMI)的发生率、后遗症、随访情况及恢复率。

研究设计

回顾性病例对照研究。

方法

我们回顾性评估了2014年至2016年期间接受复杂主动脉弓重建术的105例新生儿。我们将发生VFMI的患者与声带运动正常的对照组患者进行了比较。按治疗组对所有人口统计学和临床变量进行描述性统计。

结果

36%的患者(n = 38)由耳鼻喉科医生评估VFMI。VFMI的发生率为22%(n = 23)。女性更易发生VFMI(p = 0.02)。VFMI患者中误吸更常见(p = 0.006)。VFMI组与对照组在年龄、体重、肺炎发生率、鼻胃管、胃造口术、住院总时长、遗传异常及再次插管方面的差异无统计学意义(p > 0.05)。单侧麻痹的患者均未行气管切开术。仅61%的患者(n = 14)接受了门诊随访。64%的患者(n = 9)症状改善或消失。改善的平均时间为4.8个月。完全恢复的平均时间为10.5个月。

结论

复杂主动脉弓重建术后VFMI相对常见。尽管VFMI患者误吸增加,但两组均未发生肺炎。单侧麻痹的患者均无需行气管切开术。大多数患者在术后5个月内VFMI有所改善。我们的数据支持VFMI诊断后需要耳鼻喉科进行随访。

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