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主动脉弓手术后的声带麻痹:预测因素及临床结局

Vocal cord paralysis after aortic arch surgery: predictors and clinical outcome.

作者信息

Ohta Noriyuki, Kuratani Toru, Hagihira Satoshi, Kazumi Ken-Ichiro, Kaneko Mitsunori, Mori Takahiko

机构信息

Department of Anesthesiology, Osaka General Medical Center, Japan.

出版信息

J Vasc Surg. 2006 Apr;43(4):721-8. doi: 10.1016/j.jvs.2005.11.054.

DOI:10.1016/j.jvs.2005.11.054
PMID:16616227
Abstract

OBJECTIVE

This study is retrospective cohort study of data on vocal cord paralysis after aortic arch surgery collected during 14 years at a general hospital. We investigated factors in the development of vocal cord paralysis after aortic arch surgery and the effect of vocal cord paralysis on clinical course and outcome.

METHODS

We reviewed data for 182 patients who underwent aortic arch surgery for aortic arch aneurysm and aortic dissection between 1989 and 2003, of whom 58 patients had proximal aortic repair, 62 had distal arch repair, and 62 had total arch repair. We assessed factors associated with the development of vocal cord paralysis and examined in detail the clinical outcome of patients with vocal cord paralysis.

RESULTS

Postoperative vocal cord paralysis occurred in 40 patients. Multiple logistic regression analysis revealed the following risk factors with odds ratios (OR) for vocal cord paralysis: extension of procedures into distal arch (OR, 17.0), chronic dilatation of the aorta at the left subclavian artery (OR, 9.14), and total arch repair (OR, 4.24). Adoption of open-style stent-grafts reduced the incidence of vocal cord paralysis (OR, 0.031). The postoperative occurrence of vocal cord paralysis itself emerges as an independent predictor of pulmonary complications (OR, 4.12) and leads to a longer duration of hospital stay.

CONCLUSIONS

The risk of vocal cord paralysis after aortic arch surgery depends on surgical factors, such as aneurysmal involvement of the distal arch, or the application of newer, less invasive surgical procedures. Vocal cord paralysis after aortic arch surgery itself, under aggressive postoperative respiratory management, did not increase aspiration pneumonia but was associated with postoperative complications leading to higher hospital mortality and prolonged hospitalization.

摘要

目的

本研究是一项回顾性队列研究,收集了一家综合医院14年间主动脉弓手术后声带麻痹的数据。我们调查了主动脉弓手术后声带麻痹发生的相关因素,以及声带麻痹对临床病程和结局的影响。

方法

我们回顾了1989年至2003年间因主动脉弓瘤和主动脉夹层而接受主动脉弓手术的182例患者的数据,其中58例患者进行了主动脉近端修复,62例进行了主动脉弓远端修复,62例进行了全主动脉弓修复。我们评估了与声带麻痹发生相关的因素,并详细检查了声带麻痹患者的临床结局。

结果

40例患者术后发生声带麻痹。多因素logistic回归分析显示声带麻痹的以下危险因素及比值比(OR):手术范围扩展至主动脉弓远端(OR,17.0)、左锁骨下动脉处主动脉慢性扩张(OR,9.

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