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人类原位肝移植术后肝内胆管狭窄。原发性硬化性胆管炎复发还是同种异体移植排斥反应的特殊表现?

Intrahepatic bile duct strictures after human orthotopic liver transplantation. Recurrence of primary sclerosing cholangitis or unusual presentation of allograft rejection?

作者信息

Lerut J, Demetris A J, Stieber A C, Marsh J W, Gordon R D, Esquivel C O, Iwatsuki S, Starzl T E

机构信息

Department of Surgery, University Health Center of Pittsburgh, PA 15213.

出版信息

Transpl Int. 1988 Oct;1(3):127-30.

Abstract

One of 55 patients transplanted for sclerosing cholangitis during the cyclosporin-steroid era (March 1980-June 1986) developed intrahepatic biliary strictures in the absence of allograft rejection within the 1st year posttransplantation. Although many causes underlie biliary pathology in the postoperative period (i.e., arterial injury, ischemia, chronic rejection, cholangitis), recurrent disease remains a possibility.

摘要

在环孢素 - 类固醇时代(1980年3月 - 1986年6月)接受硬化性胆管炎移植的55例患者中,有1例在移植后第1年内出现肝内胆管狭窄,且无移植排斥反应。虽然术后胆道病理有多种原因(即动脉损伤、缺血、慢性排斥反应、胆管炎),但疾病复发仍有可能。

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