Lerut J, Demetris A J, Stieber A C, Marsh J W, Gordon R D, Esquivel C O, Iwatsuki S, Starzl T E
Department of Surgery, University Health Center of Pittsburgh, PA 15213.
Transpl Int. 1988 Oct;1(3):127-30.
One of 55 patients transplanted for sclerosing cholangitis during the cyclosporin-steroid era (March 1980-June 1986) developed intrahepatic biliary strictures in the absence of allograft rejection within the 1st year posttransplantation. Although many causes underlie biliary pathology in the postoperative period (i.e., arterial injury, ischemia, chronic rejection, cholangitis), recurrent disease remains a possibility.
在环孢素 - 类固醇时代(1980年3月 - 1986年6月)接受硬化性胆管炎移植的55例患者中,有1例在移植后第1年内出现肝内胆管狭窄,且无移植排斥反应。虽然术后胆道病理有多种原因(即动脉损伤、缺血、慢性排斥反应、胆管炎),但疾病复发仍有可能。