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阿莫西林结晶尿:一种常用抗生素的罕见副作用。

Amoxicillin Crystalluria: A Rare Side-Effect of a Commonly Prescribed Antibiotic.

作者信息

Couto Joana, Dos Santos Luis Pontes, Alves Joana Carlos, López Raquel, Maldonado Cristina

机构信息

Department of Internal Medicine 1, Unidade Local de Saúde do Alto Minho, EPE, Portugal.

Laboratory Department, Unidade Local de Saúde do Alto Minho, EPE, Portugal.

出版信息

Eur J Case Rep Intern Med. 2017 Oct 23;4(10):000736. doi: 10.12890/2017_000736. eCollection 2017.

Abstract

UNLABELLED

Although crystalluria is a frequent finding in the routine examination of urine, amoxicillin crystalluria is a rare event whose incidence remains unknown. Crystalluria caused by amoxicillin is very uncommon and may be asymptomatic or have severe renal implications. The authors describe the case of an 87-year-old female patient who presented with massive amoxicillin crystalluria due to poor hydration, low urinary pH and high intravenous amoxicillin dosage.

LEARNING POINTS

Amoxicillin crystalluria is a rare event.It can range from a transient asymptomatic crystalluria without renal damage to major haematuria or acute renal failure.We should be aware of this complication because high intravenous doses of amoxicillin are frequently prescribed and measures can be adopted to prevent this complication.

摘要

未标注

虽然结晶尿在尿液常规检查中很常见,但阿莫西林结晶尿是一种罕见事件,其发生率尚不清楚。由阿莫西林引起的结晶尿非常罕见,可能无症状或对肾脏有严重影响。作者描述了一名87岁女性患者的病例,该患者因水化不足、尿液pH值低和静脉注射阿莫西林剂量高而出现大量阿莫西林结晶尿。

学习要点

阿莫西林结晶尿是一种罕见事件。它的表现范围可从无肾损伤的短暂无症状结晶尿到严重血尿或急性肾衰竭。我们应该意识到这种并发症,因为经常会开出高剂量静脉注射阿莫西林的处方,并且可以采取措施预防这种并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ace1/6346802/51440ea6018b/736_Fig1.jpg

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