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牙源性颌面部感染的需氧和厌氧微生物及抗生素敏感性。

Aerobic and anaerobic microorganisms and antibiotic sensitivity of odontogenic maxillofacial infections.

机构信息

Endodontics Posgraduated Program, Faculty of Dentistry, San Luis Potosí University, San Luis Potosí, SLP, Mexico.

Department of Oral and Maxillofacial Surgery, Hospital "Ignacio Morones Prieto", San Luis Potosí, SLP, Mexico.

出版信息

Odontology. 2019 Jul;107(3):409-417. doi: 10.1007/s10266-019-00414-w. Epub 2019 Feb 13.

Abstract

This study aimed to identify the aerobic and anaerobic causal microorganisms of odontogenic infections and their antibiotic sensitivity. Purulent exudates were taken from patients with odontogenic infections by transdermal puncture, and aerobic and anaerobic microorganisms were identified using biochemical tests. Susceptibility to antibiotics was tested using the Kirby-Bauer method; the inhibition halos were measured according to NCCLS, and based on the results, the microorganisms were classified as susceptible, intermediate or resistant to each antibiotic. Frequencies of species and percentages of resistance were calculated. The microorganisms associated with odontogenic infections were principally anaerobic (65.3% anaerobic vs. 35.7% aerobic), and the susceptibility to antibiotics was higher in anaerobic than in aerobic microorganisms. The majority of isolated microorganisms (82%) showed susceptibility to amoxicillin/clavulanic acid. The causal agents of odontogenic infections were anaerobic microorganisms, which exhibited high resistance to antibiotics.

摘要

本研究旨在鉴定牙源性感染的需氧和厌氧病因微生物及其抗生素敏感性。通过经皮穿刺从牙源性感染患者中获取脓性渗出物,并使用生化试验鉴定需氧和厌氧微生物。使用 Kirby-Bauer 法测试抗生素敏感性;根据 NCCLS 测量抑菌环,并根据结果将微生物分类为对每种抗生素敏感、中介或耐药。计算了物种频率和耐药百分比。与牙源性感染相关的微生物主要为厌氧菌(65.3%的厌氧菌与 35.7%的需氧菌),且厌氧菌对抗生素的敏感性高于需氧菌。大多数分离的微生物(82%)对阿莫西林/克拉维酸敏感。牙源性感染的病原体为厌氧菌,对大多数抗生素具有较高的耐药性。

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