Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Department of Obstetrics and Gynecology, University of Washington School of Medicine, 1959 NE Pacific St., Box 356460, Seattle, WA, 98195-6460, USA.
Arch Womens Ment Health. 2020 Feb;23(1):1-10. doi: 10.1007/s00737-019-0950-6. Epub 2019 Feb 13.
Depression in women is more common during perimenopause (the transition to menopause) than at other times in the life cycle. Symptoms of depression may be different in perimenopausal women compared to younger or older women, and are often dismissed as part of normal menopause. This is an expert narrative review. There are several evidence-based screening modalities which can be integrated into routine women's health visits, and can facilitate distinguishing between depression and normal perimenopausal symptoms. There is emerging evidence regarding the effect of hormonal changes on the development of perimenopausal depression and its optimal treatment, though critical research gaps remain. Obstetrician-gynecologists and other primary care providers play a vital role in the detection and management of depression in women. Providers caring for women during perimenopause have a unique opportunity to diagnose depression in their patients and identify appropriate treatment options.
女性在围绝经期（绝经过渡时期）比生命周期中的其他时期更常见抑郁。与年轻或老年女性相比，围绝经期女性的抑郁症状可能不同，而且常常被视为正常绝经的一部分而被忽视。这是一篇专家叙述性评论。有几种基于证据的筛查方法可以整合到常规的妇女健康检查中，有助于区分抑郁和正常围绝经期症状。关于激素变化对围绝经期抑郁的发展及其最佳治疗的影响，有新的证据，但仍存在关键的研究空白。妇产科医生和其他初级保健提供者在女性抑郁的检测和管理中发挥着至关重要的作用。在围绝经期照顾女性的医护人员有独特的机会诊断患者的抑郁，并确定适当的治疗方案。
