由H-2抗原产生的细胞毒性淋巴细胞克隆的频率。
The frequency of clones of cytotoxic lymphocytes generated by H-2 antigens.
作者信息
Marbrook J, Nawa Y, Miller J F
出版信息
J Exp Med. 1978 Jul 1;148(1):324-8. doi: 10.1084/jem.148.1.324.
Abstract
By using a culture system that allows the segregation of individual precursors of cytotoxic lymphocytes, the number of clones generated by cells from different combinations of congenic mice have been measured. It has been found that 0.3% of the total anti-H2d clones are generated by stimulators which differ predominantly at the H-2 locus. The contribution of non-H-2 antigens to anti-H-2 responses is discussed.
摘要
通过使用一种能够分离细胞毒性淋巴细胞单个前体的培养系统，已经测定了来自同源小鼠不同组合的细胞所产生的克隆数量。已发现，在总的抗H2d克隆中，有0.3%是由主要在H-2位点存在差异的刺激物产生的。文中还讨论了非H-2抗原对抗H-2反应的贡献。
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