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基因组不稳定性在人类肿瘤发生中的作用。

Role of genomic instability in human carcinogenesis.

机构信息

1 JS Yoon Memorial Cancer Research Institute LLC, Lutherville, MD 2109, USA.

2 Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins Medical Institution, Baltimore, MD 21205, USA.

出版信息

Exp Biol Med (Maywood). 2019 Mar;244(3):227-240. doi: 10.1177/1535370219826031. Epub 2019 Feb 13.

Abstract

This review provides various genetic and cell line data previously published in a way to explain how cellular stress can lead into genetic instability.

摘要

这篇综述以一种方式提供了先前发表的各种遗传和细胞系数据,以解释细胞应激如何导致遗传不稳定性。

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