Department of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Department of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Can J Cardiol. 2019 Feb;35(2):230.e1-230.e3. doi: 10.1016/j.cjca.2018.11.030. Epub 2018 Dec 5.
We report the first case of coronary artery fistula with aneurysmal change in a patient with immunoglobulin G4-related disease (IgG4-RD). This case revealed concomitant coronary artery dilation, pericardial inflammatory nodules, and coronary-pulmonary fistula aneurysm in addition to several IgG4-RD lesions. Each of these features was located in close proximity to the thickened pericardium. These lesions might result from inflammation of the pericardial space, which extended to the coronary-pulmonary artery vessels, leading to aneurysmal formation. This case will enhance our understanding of the pathological mechanisms of IgG4-RD inflammation.
我们报告了首例 IgG4 相关疾病（IgG4-RD）患者合并冠状动脉瘘和动脉瘤样改变的病例。该病例除了多个 IgG4-RD 病变外，还显示出冠状动脉扩张、心包炎性结节和冠状肺动脉瘘动脉瘤。这些特征均位于心包增厚部位附近。这些病变可能是由于心包腔炎症扩展到冠状肺动脉血管，导致动脉瘤形成。该病例将增强我们对 IgG4-RD 炎症病理机制的理解。
