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[各种类型尿流改道术的根治性膀胱切除术的术中并发症]

[Intraoperative complications of radical cystectomy with various types of urinary diver- sions].

作者信息

Musayev T N, Guliev F A

机构信息

National Oncology Center, Azerbaijan, Baku.

出版信息

Urologiia. 2018 Oct(4):102-105.

Abstract

AIM

To investigate the rates, types and risk factors for intraoperative complications in patients with bladder cancer undergoing radical cystectomy with various types of urinary diversions.

MATERIAL AND METHODS

The study comprised 257 patients, including 241 (93.8%) men and 16 (6.2%) women who underwent radical cystectomy. The mean age of the patients was 58.5 (37-81) years. The analysis included intraoperative blood loss and blood transfusion, the rates of vascular, rectum and nerve injury, and operative time as a function of type of urinary diversion and cystectomy, the type of surgery, tumor stage (pT and pN), body mass index, and the total number of radical cystectomies performed by the surgical team.

RESULTS

Intraoperative mortality was 0.4%. Intraoperative complications were registered in 34 (13.2%) patients. The mean blood loss was 597 (100-2500) ml, mean volume of intra- and perioperative blood transfusion was 950 and 310 ml, respectively. Statistically significant predictors of intraoperative blood loss were body mass index (p=0.001), the surgeons experience (p=0.004) and the presence of lymph node metastases (N+) (p=0.033). A significant factor affecting the rate of rectal injury is a stage pT4 disease (p=0.028). Nerve injury rates did not differ statistically significantly depending on the above factors (p>0.05).

CONCLUSION

Patients with locally advanced bladder cancer and high body mass index should be operated on by highly qualified surgeons performing at least 50 radical cystectomies per year.

摘要

目的

探讨接受各种类型尿流改道的根治性膀胱切除术患者术中并发症的发生率、类型及危险因素。

材料与方法

本研究纳入257例患者,其中241例(93.8%)为男性,16例(6.2%)为女性,均接受了根治性膀胱切除术。患者的平均年龄为58.5岁(37 - 81岁)。分析内容包括术中失血及输血情况、血管、直肠和神经损伤的发生率,以及作为尿流改道和膀胱切除术类型、手术方式、肿瘤分期(pT和pN)、体重指数以及手术团队进行的根治性膀胱切除术总数函数的手术时间。

结果

术中死亡率为0.4%。34例(13.2%)患者出现术中并发症。平均失血量为597毫升(100 - 2500毫升),术中和围手术期平均输血量分别为950毫升和310毫升。术中失血的统计学显著预测因素为体重指数(p = 0.001)、外科医生经验(p = 0.004)和存在淋巴结转移(N +)(p = 0.033)。影响直肠损伤发生率的一个重要因素是pT4期疾病(p = 0.028)。神经损伤发生率在上述因素方面无统计学显著差异(p>0.05)。

结论

局部晚期膀胱癌且体重指数高的患者应由每年至少进行50例根治性膀胱切除术的高素质外科医生进行手术。

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