头部外伤合并原发性颅顶淋巴瘤：一例报告。
Head trauma complicated with primary cranial vault lymphoma: A case report.
作者信息
Huang Jie, Tang Dong, Xu Yan, Wang Xuna, Yu Chuanwen, Dong Yang
机构信息
Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian.
Department of Radiology, Hangzhou Normal University Affiliated Hospital, Hangzhou.
出版信息
Medicine (Baltimore). 2019 Feb;98(7):e14465. doi: 10.1097/MD.0000000000014465.
RATIONALE
Primary cranial vault lymphoma (PCVL) is an extremely rare extranodal lymphoma in the skull. This case study investigates the clinical features, so as to improve the understanding of the diagnosis and therapy.
PATIENT CONCERNS
A 31-year-old male presented painful scalp mass at the site of 1-month-old head trauma.
DIAGNOSIS
The final diagnosis was plasma cell lymphoma, which is a rare subtype of diffuse large B-cell lymphoma based on biopsy and immunohistochemistry findings.
INTERVENTIONS
The patient received total tumor resection in combination with chemotherapy OUTCOMES:: The patient survived without signs of systemic dissemination for 12 months after surgery at the time of last follow-up.
LESSONS
Trauma may be one of the factors that induce PCVL. The final diagnosis of PCVL depends on pathology and immunohistochemistry findings. A combined treatment of surgery, chemotherapy, and radiotherapy can achieve favorable outcomes.
原理
原发性颅顶淋巴瘤（PCVL）是一种极其罕见的颅骨结外淋巴瘤。本病例研究旨在调查其临床特征，以增进对诊断和治疗的理解。
患者情况
一名31岁男性在1个月前头部外伤部位出现头皮疼痛性肿块。
诊断
根据活检和免疫组化结果，最终诊断为浆细胞淋巴瘤，这是弥漫性大B细胞淋巴瘤的一种罕见亚型。
干预措施
患者接受了肿瘤全切术并联合化疗。
结果
在最后一次随访时，患者术后存活12个月，无全身播散迹象。
经验教训
创伤可能是诱发PCVL的因素之一。PCVL的最终诊断取决于病理和免疫组化结果。手术、化疗和放疗联合治疗可取得良好疗效。
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