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[维生素D缺乏与佝偻病:筛查与治疗,临床医生的实践要点]

[Vitamin D deficiency and rickets : screening and treatment, practical aspects for clinicians].

作者信息

Gonzalez Nguyen-Tang Elsa, Parvex Paloma, Goischke Alexandra, Wilhelm-Bals Alexandra

机构信息

Unité romande de néphrologie pédiatrique, Hôpital des enfants, 1211 Genève 4.

出版信息

Rev Med Suisse. 2019 Feb 13;15(638):384-389.

Abstract

Vitamin D deficiency is increasing in Switzerland. If cases of rickets are scarce, pediatricians are often dealing with patients presenting vitamin D deficiency. The increase in vitamin D deficiency is certainly due to modification of life habits in recent decades. Clinical presentation varies according to age and severity of deficit. Treatments differ based on the level of vitamin D deficiency and symptoms. Vitamin D deficiency rickets is the most common cause of rickets and is predominantly seen in patients with risks factors They are other types of rickets like pseudo-vitamin D deficiency and hypophosphatemic rickets that the clinician needs to recognize. In which situation should the clinician suspect vitamin D deficiency or rickets ? Different types of rickets and practical aspects of treatment are reviewed in this article.

摘要

瑞士维生素D缺乏症的发病率正在上升。由于佝偻病病例较少,儿科医生经常诊治维生素D缺乏的患者。维生素D缺乏症的增加肯定归因于近几十年来生活习惯的改变。临床表现因年龄和缺乏程度而异。治疗方法根据维生素D缺乏水平和症状而有所不同。维生素D缺乏性佝偻病是佝偻病最常见的病因,主要见于有风险因素的患者。临床医生还需要识别其他类型的佝偻病,如假性维生素D缺乏症和低磷血症性佝偻病。临床医生在哪些情况下应怀疑维生素D缺乏或佝偻病?本文将对不同类型的佝偻病及治疗的实际问题进行综述。

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