Kochetkova A A, Vorobyeva I S, Vorobyeva V M, Sharafetdinov Kh Kh, Plotnikova O A, Pilipenko V V, Alexeeva R I, Sasunova A N
Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow.
Vopr Pitan. 2018;87(6):76-88. doi: 10.24411/0042-8833-2018-10069. Epub 2018 Nov 13.
In recent years, the incidence of diabetes mellitus (DM) in the world is growing steadily. According to the international diabetes Federation (IDF), the number of DM patients in the world in 2015 was 415 million, of them more than 90% - patients with type 2 diabetes. According to forecasts, in 2040 their number will increase to 642 million. Russia ranks fifth among the ten countries with the largest number of the adult population with diabetes. Dietary correction of the diet of patients with type 2 DM is carried out by the inclusion of specialized foods with a modified carbohydrate profile containing ingredients with hypoglycemic action. The purpose of the study - the development of composition and technology of specialized foods and assessment of the possibility of their use in the therapy of patients with type 2 diabetes. Taking into account the medical requirements for diet therapy for type 2 diabetes, composition and technology of two specialized foods in the form of beverage concentrates have been developed. The technology of step-bystep mixing contributed to the uniform distribution of biologically active substances in the mass of the product. The absence of sucrose and digestible polysaccharides in the composition of the developed products was established, the presence of about 1% lactose was due to its content in the protein component. Humidity didn't exceed the standard values for similar products, the values water activity were typical for products with low humidity, which justified the prediction of the microbiological stability of the developed products during storage. The osmolality of the beverages restored in accordance with the method of preparation was 310 and 258 mOsm/kg, which characterized them as isotonic. The products were balanced in amino acid composition, had a high score of essential amino acids due to the introduction of a combination of proteins. The consumption of one serving (30 g) of the product in the form of a drink (200 ml) provided an average daily requirement for essential amino acids by 15-22%, polyunsaturated fatty acids ω-3 - by 10%, ω-6 - by 15%, soluble dietary fibers - by 50-55%, vitamins groups B - by 14-81%, C - by 46%, A, D, E, K - by 17-46%, minerals and trace elements - by 10- 33%. The content of polyphenols was about a half of its adequate level of consumption. The inclusion of specialized foods with a modified carbohydrate profile in the composition of the low-calorie diet lead to the stabilization of postprandial blood glucose levels in patients with type 2 DM.
近年来,全球糖尿病(DM)的发病率在稳步上升。根据国际糖尿病联盟(IDF)的数据,2015年全球糖尿病患者人数为4.15亿,其中90%以上为2型糖尿病患者。据预测,到2040年这一数字将增至6.42亿。在成年糖尿病患者人数最多的十个国家中,俄罗斯排名第五。对2型糖尿病患者的饮食进行膳食调整,是通过纳入碳水化合物成分经过改良、含有具有降血糖作用成分的特殊食品来实现的。本研究的目的——研发特殊食品的成分和工艺,并评估其用于2型糖尿病患者治疗的可能性。考虑到2型糖尿病饮食治疗的医学要求,已研发出两种浓缩饮料形式的特殊食品的成分和工艺。逐步混合工艺有助于生物活性物质在产品整体中均匀分布。已确定所研发产品的成分中不含蔗糖和可消化多糖,约1%乳糖的存在是因其在蛋白质成分中的含量。湿度未超过同类产品的标准值,水分活度值对于低湿度产品来说是典型的,这证明所研发产品在储存期间微生物稳定性的预测是合理的。按照制备方法复原后的饮料渗透压分别为310和258 mOsm/kg,表明它们为等渗溶液。这些产品的氨基酸组成均衡,由于引入了多种蛋白质,必需氨基酸得分较高。饮用一份(30克)该产品制成的饮料(200毫升),可满足人体每日必需氨基酸平均需求量的15 - 22%、多不饱和脂肪酸ω - 3的10%、ω - 6的15%、可溶性膳食纤维的50 - 55%、B族维生素的14 - 81%、维生素C的46%、维生素A、D、E、K的17 - 46%以及矿物质和微量元素的10 - 33%。多酚含量约为适宜摄入量的一半。在低热量饮食中纳入碳水化合物成分经过改良的特殊食品,可使2型糖尿病患者餐后血糖水平趋于稳定。