Mladěnka A, Sláma J
Ceska Gynekol. 2018 Winter;83(3):218-225.
Overview of available information on current vaccination options against HPV and possibilities for further development.
Review article.
Clinic of Gynecology and Obstetrics, University Hospital in Ostrava; Clinic of Gynecology and Obstetrics, General University Hospital in Prague.
Three prophylactic vaccines have been developed against HPV infection and are all now avaliable in Czech Repulbic; nonavalent (Gardasil 9), quadrivalent vaccine (Silgard) and bivalent vaccine (Cervarix). Therapeutic vaccines, designed to induce regression of existing HPV-associated lesions, are in development and not yet clinically available.
All three avaliable prophylactic vaccines show high efficacy in prevention of vaccine-specific HPV-type infection. The highest degree of protection is achieved in the population of HPV-naive women.
概述目前针对人乳头瘤病毒（HPV）的疫苗接种选择及进一步发展的可能性。
综述文章。
俄斯特拉发大学医院妇产科诊所；布拉格综合大学医院妇产科诊所。
已研发出三种预防HPV感染的疫苗，目前在捷克共和国均可获得；九价疫苗（佳达修9）、四价疫苗（希瑞适）和二价疫苗（卉妍康）。旨在促使现有HPV相关病变消退的治疗性疫苗正在研发中，尚未应用于临床。
所有三种可用的预防性疫苗在预防疫苗特定型HPV感染方面均显示出高效性。HPV初筛阴性的女性群体可获得最高程度的保护。
