State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Xiamen University, Xiamen, Fujian, China; Key Laboratory of Health Technology Assessment of Fujian Province, School of Public Health, Xiamen University, China.
Department of Public Health, Tzu-Chi University, Taiwan.
Vaccine. 2019 Mar 7;37(11):1449-1456. doi: 10.1016/j.vaccine.2019.01.071. Epub 2019 Feb 12.
The impact of influenza in children under 5 can be severe and fatal. However, the influenza vaccination uptake in China remains suboptimal. The objectives of this study were to investigate parents' perceptions on influenza vaccination and to assess vaccination promotional factors.
A cross-sectional survey among 1506 parents with children in kindergarten was conducted in two areas with different policies: self-paid vaccination and free vaccination. The questionnaire was based on the structure of the Health Belief Model (HBM). Multiple logistic regression was used to analyze the determinants of parental vaccination intention. Odds ratios (OR) and respective 95% confidence intervals (95% CI) are reported.
Within the free policy group versus the non-free group, vaccination intention rates were 76.3% versus 83.4%, and vaccination rates were 34.2% versus 3.1%. Results from multivariate analysis showed that parents with high scores for perceived susceptibility (OR = 1.44; 95% CI: 1.09-1.91), perceived benefits (OR = 1.80; 95% CI: 1.30-2.50) and cues to action (OR = 3.32; 95% CI: 2.47-4.46) were more likely to get their children vaccinated, while those perceived more barriers (OR = 0.50; 95% CI: 0.37-0.68) had lower vaccination intention. More knowledge (OR = 1.74; 95% CI: 1.18-2.56) and preferable attitudes (higher perceived necessity: OR = 1.84; 95% CI: 1.53-2.22; less safety worry: OR = 1.35; 95% CI: 1.10-1.66) were associated with significantly higher vaccination intention. Adjusted for parents' gender, age, education, income and children's age, the same significant factors were found. Parental intention was found to be influenced by different vaccination policies. Under a free policy, past influenza vaccination uptake (OR = 4.52; 95% CI: 1.07-19.02) greatly promoted parents' willingness to vaccinate their children.
Parents had high intention to get their kindergarten children vaccinated with the influenza vaccine in spite of the low uptake rate. Our results indicate that offering free influenza vaccines and parental education over the next years may increase the influenza vaccination rate.
5 岁以下儿童患流感可能会很严重,甚至致命。然而,中国的流感疫苗接种率仍然不理想。本研究旨在调查家长对流感疫苗接种的看法,并评估疫苗推广因素。
在两个政策不同的地区(自费接种和免费接种)对 1506 名幼儿园儿童的家长进行了横断面调查。问卷以健康信念模型(HBM)的结构为基础。采用多因素 logistic 回归分析父母接种意愿的决定因素。报告比值比(OR)及其 95%置信区间(95%CI)。
在免费政策组与非免费政策组中,接种意愿率分别为 76.3%和 83.4%,接种率分别为 34.2%和 3.1%。多因素分析结果显示,对易感性(OR=1.44;95%CI:1.09-1.91)、获益(OR=1.80;95%CI:1.30-2.50)和行动提示(OR=3.32;95%CI:2.47-4.46)感知较高的父母更有可能为孩子接种疫苗,而感知障碍较多的父母(OR=0.50;95%CI:0.37-0.68)接种意愿较低。更多的知识(OR=1.74;95%CI:1.18-2.56)和更好的态度(感知必要性更高:OR=1.84;95%CI:1.53-2.22;安全性担忧减少:OR=1.35;95%CI:1.10-1.66)与更高的接种意愿显著相关。调整父母的性别、年龄、教育、收入和孩子的年龄后,仍发现相同的显著因素。父母的意愿受到不同疫苗接种政策的影响。在免费政策下,既往流感疫苗接种率(OR=4.52;95%CI:1.07-19.02)极大地促进了父母为子女接种疫苗的意愿。
尽管接种率较低,但家长对为幼儿园儿童接种流感疫苗的意愿很高。我们的研究结果表明,在未来几年内提供免费流感疫苗和家长教育可能会提高流感疫苗接种率。