Kawai Hiroshi, Mizuno Daisuke, Yoshikawa Chihiro, Mushiake Yutaka, Kawasaki Kento, Iga Norichika, Yoshida Ryosuke, Waki Naohisa, Uno Futoshi, Ishizaki Masahiro, Nishi Hideyuki, Yamashita Kazuki, Miyoshi Shinichiro, Sonobe Hiroshi
Dept. of Surgery, Okayama Rosai Hospital.
Gan To Kagaku Ryoho. 2019 Jan;46(1):154-156.
A 66-year-old woman underwent distal gastrectomy because of gastric cancer(stage ⅠB)and received no adjuvant chemotherapy. Eight years after the operation, computed tomography showed a small nodule in the right breast. Mammography did not reveal any abnormalities. Ultrasound sonography showed a diffuse and gradual non-mass-like low echoic lesion. Core needle biopsy indicated a malignancy. Partial resection of the right breast was performed to obtain a diagnosis. On postoperative histopathological examination, signet-ring cells were found in the tumor, and immunohistochemical analysis showed that both the breast tumor and the gastric carcinoma were MUC5AC-positive and MUC1-negative. We diagnosed this breast tumor as metastasis from gastric cancer. The patient has received chemotherapy with no subsequent metastatic tumors, and good control has been achieved for 21 months after the detection of the breast metastasis.
一名66岁女性因胃癌（ⅠB期）接受了远端胃切除术，未接受辅助化疗。术后八年，计算机断层扫描显示右乳有一个小结节。乳房X线摄影未发现任何异常。超声检查显示为弥漫性、渐进性的非肿块样低回声病变。空心针活检提示为恶性肿瘤。为明确诊断，对右乳进行了部分切除术。术后组织病理学检查发现肿瘤中有印戒细胞，免疫组化分析显示乳腺肿瘤和胃癌均为MUC5AC阳性、MUC1阴性。我们将该乳腺肿瘤诊断为胃癌转移。患者接受了化疗，此后未出现转移性肿瘤，在发现乳腺转移后21个月病情得到了良好控制。
