吉西他滨联合纳米白蛋白紫杉醇治疗后肝转移胰头癌的根治性切除
[Curative Resection of Pancreatic Head Cancer with Liver Metastasis after GEM plus Nab-PTX Therapy].
作者信息
Yotsumoto Hirokazu, Yamamoto Naoto, Kamiya Mariko, Inoue Hirohide, Murakawa Masaaki, Aoyama Toru, Numata Masakatsu, Hayashi Tsutomu, Yamada Takanobu, Ohshima Takashi, Shiozawa Manabu, Rino Yasushi, Masuda Munetaka, Morinaga Soichiro
机构信息
Dept. of Gastrointestinal Surgery, Kanagawa Cancer Center.
出版信息
Gan To Kagaku Ryoho. 2019 Jan;46(1):169-171.
A 63-year-old man was admitted to our hospital for examination and treatment of a pancreatic head tumor detected at a nearby hospital. After CT, EUS-FNA, and PET-CT, he was diagnosed with unresectable pancreatic cancer with liver metastasis. After 9 courses of gemcitabine and nab-paclitaxel therapy, the primary tumor was dramatically reduced in size and the liver metastasis had disappeared. He underwent subtotal stomach-preserving pancreaticoduodenectomy. The postoperative diagnosis according to the General Rules of the Study of Pancreatic Cancer(7th edition)was Ph, TS1(15mm), adenosquamous carcinoma, ypT3, ypRP1, ypPL1, R0, ypN0(0/29), M0, CY0, ypStage ⅡA. The histological response was Grade 2. The patient remains alive without recurrence 5 months after surgical resection.
一名63岁男性因在附近医院检查发现胰头肿瘤而入住我院接受治疗。经过CT、EUS-FNA和PET-CT检查后，他被诊断为无法切除的胰腺癌伴肝转移。在接受9个疗程的吉西他滨和纳米白蛋白结合型紫杉醇治疗后，原发肿瘤大小显著缩小，肝转移灶消失。他接受了保留大部分胃的胰十二指肠切除术。根据《胰腺癌研究总则》（第7版），术后诊断为Ph、TS1（15mm）、腺鳞癌、ypT3、ypRP1、ypPL1、R0、ypN0（0/29）、M0、CY0、ypⅡA期。组织学反应为2级。手术切除后5个月，患者仍存活且无复发。
Zotero 插件