微孔多糖微球在初次全膝关节置换术中的疗效与安全性。
Microporous polysaccharide hemosphere efficacy and safety in primary total knee arthroplasty.
作者信息
Gleason Scott, Mehl David, Payne William, Parry Steve, Stein Amy Buros
机构信息
Midwestern University/Franciscan St. James Health, 20201 South Crawford Ave, Olympia Fields, IL, 60461, USA.
Midwestern University, 19555 North 59th Ave, Glendale, AZ, 85308, USA.
出版信息
J Orthop. 2018 Dec 6;16(1):19-24. doi: 10.1016/j.jor.2018.11.006. eCollection 2019 Jan-Feb.
Abstract
Absorbable hemostats such as microporous polysaccharide hemospheres (MPH) are used to manage hemostasis and prevent complications in total knee arthroplasty (TKA). We aimed to determine safety and effectiveness of MPH use in TKA. Records were reviewed for blood loss, hematomas, and infections. No differences existed regarding demographics, superficial infections (P = 0.933) or hematomas (P = 0.393). Positive correlation existed between hematoma and superficial infection (P = 0.009). Blood loss was greater in the treatment group (P = 0.014). MPH demonstrated inferior bleeding control and had no effect on complications. Our results suggest application of this agent may be unnecessary.
摘要
可吸收止血剂，如微孔多糖微球（MPH），用于全膝关节置换术（TKA）中的止血和预防并发症。我们旨在确定MPH在TKA中使用的安全性和有效性。回顾记录以了解失血、血肿和感染情况。在人口统计学、浅表感染（P = 0.933）或血肿（P = 0.393）方面不存在差异。血肿与浅表感染之间存在正相关（P = 0.009）。治疗组的失血量更大（P = 0.014）。MPH显示出较差的出血控制效果，且对并发症没有影响。我们的结果表明，可能无需应用这种药物。
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