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单侧先天性鼻泪管阻塞是一种致弱视因素吗?

Unilateral Congenital Nasolacrimal Duct Obstruction, Is It An Amblyogenic Factor?

作者信息

AlHammad Fatimah, Al Tamimi Elham, Yassin Sanaa, AlBadri Khadija, AlJarudi Saleh, AlShawaf Mohammed, Khandekar Rajiv

机构信息

Oculoplastic and Orbit Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Department of Ophthalmology, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.

出版信息

Middle East Afr J Ophthalmol. 2018 Jul-Dec;25(3-4):156-160. doi: 10.4103/meajo.MEAJO_3_17.

DOI:10.4103/meajo.MEAJO_3_17
PMID:30765954
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6348941/
Abstract

BACKGROUND/AIMS: To evaluate the refractive status, axial length, and prevalence of amblyopia among Saudi children with unilateral congenital nasolacrimal duct obstruction (UCNLDO) compared to the unaffected fellow eye.

METHODS

A retrospective chart review was performed for children with UCNLDO at two eye institutes in Eastern Saudi Arabia from 2009 to 2015. The outcomes of syringing determined UNCLDO. The risk factors for amblyopia were defined as anisometropia of (spherical equivalent) >1.5 D, hyperopia >3.5 D, myopia >3.0 D, astigmatism >1.5 D at 90° or 180°, >1.0 D, any manifest strabismus, any media opacity >1 mm, or ptosis 1 mm or less margin reflex distance 1 along with blunting of vision in that eye. Matched-pair analysis was performed to correlate variables. < 0.05 was considered statistically significant.

RESULTS

We included 39 children with UNCLDO. The mean axial length was 21.4 ± 1.3 mm for the eyes with UCNLDO and 21.6 ± 1.0 mm for the fellow eye ( = 0.4). Hyperopia >+2 D was present in 17 (44%) eyes with UCNLDO and none of the fellow eyes. None of the participants had strabismus.

CONCLUSION

Axial length and risk factors of amblyopia such as anisometropia, hyperopia, and strabismus were not associated with UCNLDO. UCNLDO is likely an isolated defect.

摘要

背景/目的:评估沙特患有单侧先天性鼻泪管阻塞(UCNLDO)儿童的屈光状态、眼轴长度以及弱视患病率,并与未受影响的对侧眼进行比较。

方法

对2009年至2015年沙特东部两家眼科机构中患有UCNLDO的儿童进行回顾性病历审查。通过冲洗结果确定UCNLDO。弱视的危险因素定义为(等效球镜)屈光参差>1.5D、远视>+3.5D、近视>-3.0D、90°或180°处散光>1.5D、>1.0D、任何明显斜视、任何介质混浊>1mm、或上睑下垂1mm或更少(缘反射距离1)以及该眼视力减退。进行配对分析以关联变量。P<0.05被认为具有统计学意义。

结果

我们纳入了39例患有UCNLDO的儿童。患有UCNLDO的眼睛平均眼轴长度为21.4±1.3mm,对侧眼为21.6±1.0mm(P = 0.4)。17只(44%)患有UCNLDO的眼睛存在>+2D的远视,对侧眼均无。所有参与者均无斜视。

结论

眼轴长度以及弱视的危险因素如屈光参差、远视和斜视与UCNLDO无关。UCNLDO可能是一种孤立的缺陷。

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本文引用的文献

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A clinic-based study of refractive errors, strabismus, and amblyopia in pediatric age-group.一项针对儿童年龄组屈光不正、斜视和弱视的基于诊所的研究。
J Family Community Med. 2015 Sep-Dec;22(3):158-62. doi: 10.4103/2230-8229.163031.
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Axial Globe Length in Congenital Ptosis.
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The prevalence of amblyogenic factors in children with persistent congenital nasolacrimal duct obstruction.持续性先天性鼻泪管阻塞患儿中致弱视因素的患病率。
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Pediatric nasolacrimal duct obstruction.小儿鼻泪管阻塞。
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Anisometropia and amblyopia in nasolacrimal duct obstruction.鼻泪管阻塞中的屈光参差和弱视
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