Regenbogen L, Coscas G, Debbasch S
Maurice and Gabriela Goldschleger Eye Institute, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Metab Pediatr Syst Ophthalmol (1985). 1988;11(1-2):14-28.
Research in genetics and the collaboration of various medical disciplines are responsible for the discovery of many new syndromes. The association of ocular and skin malformations is not astonishing when one remembers that the embryonic development of the eye and the skin are of ectodermal origin; both the eye and skin may reflect a variety of systemic disturbances occurring during their formation, or represent genetic disorders. An ocular and a dermatological feature may be the first indication of a possible disturbance on other organs. The reality that juveniles may frequently present simultaneous associations of eye and skin malformations is a phenomenon not widely known among physicians and reports in the recognition of syndromes with those manifestations are dispersed among various medical journals. The authors described the various syndromes with ocular and dermatologic findings that are of interest to the ophthalmologist.
遗传学研究以及各医学学科间的合作促成了许多新综合征的发现。当人们想到眼睛和皮肤的胚胎发育均源于外胚层时，眼部和皮肤畸形的关联就不足为奇了；眼睛和皮肤都可能反映其形成过程中发生的各种全身性紊乱，或者代表遗传性疾病。眼部和皮肤特征可能是其他器官出现潜在紊乱的首个迹象。青少年经常同时出现眼部和皮肤畸形这一现象在医生中并不广为人知，而且关于那些表现的综合征识别报告分散在各种医学期刊中。作者描述了眼科医生感兴趣的伴有眼部和皮肤病学表现的各种综合征。
