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本文引用的文献

1
Patterns of infection and infection-related mortality in patients with steroid-refractory acute graft versus host disease.类固醇难治性急性移植物抗宿主病患者的感染模式及感染相关死亡率
Bone Marrow Transplant. 2017 Jan;52(1):107-113. doi: 10.1038/bmt.2016.225. Epub 2016 Sep 5.
2
Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America.曲霉病诊断和管理实践指南：美国感染病学会2016年更新版
Clin Infect Dis. 2016 Aug 15;63(4):e1-e60. doi: 10.1093/cid/ciw326. Epub 2016 Jun 29.
3
Emergence of Azole Resistance in Aspergillus.曲霉中唑类耐药性的出现。
Semin Respir Crit Care Med. 2015 Oct;36(5):673-80. doi: 10.1055/s-0035-1562894. Epub 2015 Sep 23.
4
Nationwide Surveillance of Azole Resistance in Aspergillus Diseases.全国范围内曲霉菌病中唑类耐药性监测
Antimicrob Agents Chemother. 2015 Aug;59(8):4569-76. doi: 10.1128/AAC.00233-15. Epub 2015 May 18.
5
Prior in vitro exposure to voriconazole confers resistance to amphotericin B in Aspergillus fumigatus biofilms.先前在体外接触伏立康唑会导致烟曲霉生物膜对两性霉素 B 产生耐药性。
Int J Antimicrob Agents. 2015 Sep;46(3):342-5. doi: 10.1016/j.ijantimicag.2015.03.006. Epub 2015 Apr 24.
6
Combination antifungal therapy for invasive aspergillosis: a randomized trial.侵袭性曲霉病的联合抗真菌治疗：一项随机试验。
Ann Intern Med. 2015 Jan 20;162(2):81-9. doi: 10.7326/M13-2508.
7
Antifungal susceptibilities of Aspergillus fumigatus clinical isolates obtained in Nagasaki, Japan.日本长崎市分离的烟曲霉临床分离株的抗真菌药敏性。
Antimicrob Agents Chemother. 2012 Jan;56(1):584-7. doi: 10.1128/AAC.05394-11. Epub 2011 Oct 24.
8
Wild-type MIC distribution and epidemiological cutoff values for Aspergillus fumigatus and three triazoles as determined by the Clinical and Laboratory Standards Institute broth microdilution methods.根据临床和实验室标准协会的肉汤微量稀释方法，确定了烟曲霉野生型 MIC 分布和三种三唑类药物的流行病学截断值。
J Clin Microbiol. 2009 Oct;47(10):3142-6. doi: 10.1128/JCM.00940-09. Epub 2009 Aug 19.
9
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Clin Microbiol Infect. 2003 Jun;9(6):467-74. doi: 10.1046/j.1469-0691.2003.00592.x.

一名56岁免疫抑制男性的致命性耐药侵袭性肺炎

Fatal Drug-Resistant Invasive Pulmonary in a 56-Year-Old Immunosuppressed Man.

作者信息

Seaburg Luke A, Hill Josh A, Albert Tyler J

机构信息

is a Physician at the Veterans Affairs Puget Sound Healthcare System in Seattle, Washington. is a Senior Fellow in the Division of Pulmonary and Critical Care Medicine, is an Acting Assistant Professor in the Division of Allergy and Infectious Disease, and Dr. Albert is a Clinical Instructor in the Division of General Internal Medicine, all in the Department of Medicine at the University of Washington School of Medicine.

出版信息

Fed Pract. 2018 Aug;35(Suppl 5):S58-S61.

PMID:30766405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6248146/
Abstract

Immune status, severity or burden of disease, appropriate dosing of medication, and drug resistance are important considerations when treating immunosuppressed patients.

摘要

在治疗免疫抑制患者时，免疫状态、疾病的严重程度或负担、药物的适当剂量以及耐药性都是需要重点考虑的因素。