Wang Yu-Hong, Tian Ye, Gao Jin-Xin, Lei Chao-Kuan, Liu Yan-Wen, Han Zhong-Min, Xing Hua, Yan Can, Zhou Le
Department of Medical Technology and Engineering, Zhengzhou Railway Vocational and Technical College, Zhengzhou, Henan, 451460, China.
College of Chemistry & Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, China.
Afr Health Sci. 2018 Dec;18(4):1109-1116. doi: 10.4314/ahs.v18i4.32.
Tuberculosis (TB) is a major public health concern worldwide, and spreads more easily in densely populated areas such as school campuses.
The aim of this study was to determine the prevalence of positive TB skin tests among freshmen, i.e. newly-enrolled college students, in Zhengzhou City, China.
We reviewed the data of purified protein derivative (PPD) skin tests in 656,212 freshmen in 2004-2013.
A positive test showed a diameter of swelling ≥ 5 mm. The PPD positive rate was 40.69 %, with a prevalence of 146.29 per 100,000. During the 10-year study period, the rate of students with positive PPD test increased from 34.19 % in 2004 to 40.69 % in 2013. The positive PPD rate was significantly higher in males than in females (41.68 % vs 39.61 %, P<0.0001), and in rural compared with urban areas (42.04 % vs 38.03 %, P<0.0001).
These findings indicated a high prevalence of PPD positivity among participants during the study period, with an increasing trend. Therefore, this population needs to be targeted by TB prevention and control programs.
结核病是全球主要的公共卫生问题，在校园等人口密集地区更容易传播。
本研究旨在确定中国郑州市大一新生（即新入学大学生）中结核菌素皮肤试验阳性的患病率。
我们回顾了2004年至2013年656212名大一新生的结核菌素纯蛋白衍生物（PPD）皮肤试验数据。
阳性试验表现为肿胀直径≥5毫米。PPD阳性率为40.69%，每10万人中有146.29人患病。在为期10年的研究期间，PPD试验阳性的学生比例从2004年的34.19%上升至2013年的40.69%。男性的PPD阳性率显著高于女性（41.68%对39.61%，P<0.0001），农村地区高于城市地区（42.04%对38.03%，P<0.0001）。
这些发现表明，在研究期间参与者中PPD阳性率较高且呈上升趋势。因此，这一人群需要成为结核病预防和控制项目的目标对象。
