Gerhardy Benjamin
Department of Thoracic Medicine The Prince Charles Hospital Brisbane Australia.
Respirol Case Rep. 2019 Feb 5;7(3):e00407. doi: 10.1002/rcr2.407. eCollection 2019 Apr.
We describe a patient with underlying HIV presenting with progressive respiratory distress and acute renal failure. A unifying diagnosis of microscopic polyangiitis was made. Following immunosuppression induction with plasma exchange and intravenous corticosteroid and subsequent maintenance immunosuppression with intravenous cyclophosphamide in conjunction with renal replacement therapy he achieved remission. To our knowledge this is the first documented case of microscopic polyangiitis occurring in the context of underlying HIV, and raises interesting possibilities regarding the development of vasculitis in this patient.
我们描述了一名患有基础HIV感染的患者，该患者出现进行性呼吸窘迫和急性肾衰竭。最终确诊为显微镜下多血管炎。在通过血浆置换和静脉注射皮质类固醇进行免疫抑制诱导，以及随后通过静脉注射环磷酰胺联合肾脏替代疗法进行维持性免疫抑制治疗后，患者病情缓解。据我们所知，这是第一例有文献记载的在基础HIV感染背景下发生显微镜下多血管炎的病例，这为该患者血管炎的发展提出了有趣的可能性。
