Troutman Gregory Scott, Salamon Jason, Scharf Matthew, Mazurek Jeremy A
Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.
Department of Medicine, Division of Cardiology, Morristown Medical Center, Atlantic Medical Group, Morristown, NJ, USA.
Case Rep Cardiol. 2019 Jan 15;2019:5845839. doi: 10.1155/2019/5845839. eCollection 2019.
Osborn waves, or J waves, initially described by John Osborn in 1953 in hypothermic dog experiments, are highly sensitive and specific for hypothermia. Initially thought to be secondary to a hypothermia-induced "injury current," they have more recently been attributed to a voltage differential between epicardial and endocardial potassium (I) currents. While the exact conditions required to induce such waves have been debated, numerous clinical scenarios of environmental and iatrogenic hypothermia have been described. Below, we report a novel case of hypothermia-that of neurosarcoidosis-induced central hypothermia with resultant Osborn waves and other associated findings found on electrocardiogram (ECG).
奥斯本波，即J波，由约翰·奥斯本于1953年在低温犬实验中首次描述，对低温具有高度敏感性和特异性。最初认为它继发于低温诱导的“损伤电流”，但最近被认为是由心外膜和心内膜钾（I）电流之间的电压差引起的。虽然诱导此类波所需的确切条件一直存在争议，但已描述了许多环境性和医源性低温的临床情况。下面，我们报告一例低温的新病例——神经结节病引起的中枢性低温，其心电图（ECG）出现了奥斯本波及其他相关表现。
