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脱水人羊膜/绒毛膜在机器人辅助子宫内膜异位症切除术中裸露输尿管愈合中的新作用

Novel Role of Dehydrated Human Amnion/Chorion Membrane in Healing of Denuded Ureter in Robot-Assisted Excision of Endometriosis.

作者信息

Hasan Osamah, Johnson Grant S, Siegert James J, Garcini Francisco, Nguyen Thai T

机构信息

Midwestern University Chicago College of Osteopathic Medicine, 555 31st St, Downers Grove, IL 60515, USA.

Franciscan Health, 20201 South Crawford Avenue, Olympia Fields, IL 60461, USA.

出版信息

Case Rep Obstet Gynecol. 2019 Jan 15;2019:1920430. doi: 10.1155/2019/1920430. eCollection 2019.

Abstract

Ureteral injury is an uncommon but potentially morbid complication following any open or endoscopic pelvic procedure. Gynecologic surgeries alone make up 50 percent of nonurologic ureteral injuries leading to prolonged hospital stays, secondary interventions, and potential loss of renal function. The use of AmnioFix ® a processed dehydrated, immunologically privileged cellular amniotic membrane allograft has been well established in urologic and gynecologic procedures. These allografts contain human extracellular matrix components, growth factors, and cytokines that mediate inflammation and facilitate would healing. We report the first application of AmnioFix on a denuded ureter during a case of robotic-assisted excision of endometriosis. We include a literature review and discussion on the management outcomes of iatrogenic injury to the ureters.

摘要

输尿管损伤是任何开放性或内镜下盆腔手术之后不常见但可能致病的并发症。仅妇科手术就占非泌尿外科输尿管损伤的50%,会导致住院时间延长、二次干预以及潜在的肾功能丧失。在泌尿外科和妇科手术中,使用AmnioFix®(一种经过处理的脱水、具有免疫特权的细胞羊膜同种异体移植物)已得到充分证实。这些同种异体移植物含有介导炎症并促进伤口愈合的人类细胞外基质成分、生长因子和细胞因子。我们报告了在机器人辅助切除子宫内膜异位症病例中首次将AmnioFix应用于裸露输尿管的情况。我们还包括对输尿管医源性损伤管理结果的文献综述和讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c86b/6350570/2d398f3865a3/CRIOG2019-1920430.001.jpg

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