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内镜超声引导下胃静脉曲张血管治疗:单中心经验

Endoscopic Ultrasound-Guided Angiotherapy for Gastric Varices: A Single Center Experience.

作者信息

Khoury Tawfik, Massarwa Muhammad, Daher Saleh, Benson Ariel A, Hazou Wadi, Israeli Eran, Jacob Harold, Epstein Julia, Safadi Rifaat

机构信息

Liver Unit Institute of Gastroenterology and Liver Diseases, Division of Internal Medicine Hebrew University-Hadassah Medical Organization Jerusalem Israel.

出版信息

Hepatol Commun. 2018 Dec 10;3(2):207-212. doi: 10.1002/hep4.1289. eCollection 2019 Feb.

Abstract

There are limited efficacious therapeutic options for management of gastric variceal bleeding. Treatment modalities include transjugular intrahepatic portosystemic shunt, surgical shunts, and endoscopic interventions, including the recent advancement of endoscopic ultrasound (EUS)-guided coiling. We present a case series of 10 patients with portal hypertension (7 with liver cirrhosis and 3 without cirrhosis), complicated by gastric varices (GV) with bleeding. All cases were treated successfully with EUS-guided coiling leading to variceal eradication. There were 10 occurrences of minimal self-limited bleeding at the puncture site during the procedure, and only one occurrence of major bleeding that necessitated cyanoacrylate glue injection for homeostasis. There were no other adverse events within a mean follow-up time of 9.7 months (range, 1-28 months). In our series, EUS-guided angiotherapy was effective for GV eradication with a high safety profile.

摘要

对于胃静脉曲张出血的管理,有效的治疗选择有限。治疗方式包括经颈静脉肝内门体分流术、外科分流术以及内镜干预,包括最近内镜超声(EUS)引导下圈套术的进展。我们报告了一组10例门静脉高压患者的病例系列(7例肝硬化患者和3例非肝硬化患者),这些患者并发胃静脉曲张(GV)并出血。所有病例均通过EUS引导下圈套术成功治疗,实现了静脉曲张根除。术中穿刺部位有10次出现轻微的自限性出血,仅1次出现大出血,需要注射氰基丙烯酸酯胶来维持止血。在平均9.7个月(范围1 - 28个月)的随访期内,没有其他不良事件发生。在我们的系列研究中,EUS引导下血管内治疗对于根除GV有效且安全性高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7051/6357835/ce0acb50892f/HEP4-3-207-g001.jpg

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