Busch Sonia, Eckardt Lars, Sommer Philipp, Meyer Christian, Bonnemeier Hendrik, Thomas Dierk, Neuberger Hans-Ruprecht, Tilz Roland Richard, Steven Daniel, von Bary Christian, Kuniss Malte, Voss Frederic, Estner Heidi L
II. Med. Klinik, Klinik für Kardiologie, Angiologie, Pneumologie, Klinikum Coburg, Ketschendorfer Str. 33, 96450, Coburg, Deutschland.
Klinik für Kardiologie II - Rhythmologie, Universitätsklinikum Münster, Münster, Deutschland.
Herzschrittmacherther Elektrophysiol. 2019 Jun;30(2):212-224. doi: 10.1007/s00399-019-0607-1. Epub 2019 Feb 14.
Premature ventricular contractions (PVC) are a common, often incidental and mostly benign finding. Treatment is indicated in frequent and symptomatic PVC or in cases of worsening of left ventricular function. Idiopathic ventricular tachycardia (VT) is mostly found in patients with a structurally healthy heart. These PVC/VT usually have a focal origin. The most likely mechanism is delayed post-depolarization. Localization of the origin is based on the creation of an activation map with or without combination of pace mapping. Idiopathic PVC/VT are most frequently located on the outflow tracts of the right and left ventricles, including the aortic root. Other typical locations include the annulus of the tricuspid or mitral valve, papillary muscles and Purkinje fibers. Catheter ablation is an alternative to antiarrhythmic medication in symptomatic monomorphic PVC/VT. The success rate is good whereby mapping and ablation can often represent a challenge. This article is the fifth part of a series dedicated to specific advanced training in the field of special rhythmology and invasive electrophysiology. It describes the pathophysiological principles, types and typical findings that can be obtained during an electrophysiological investigation.
室性早搏(PVC)很常见,通常为偶然发现,且大多为良性。对于频发且有症状的PVC或左心室功能恶化的情况,需要进行治疗。特发性室性心动过速(VT)多见于心脏结构正常的患者。这些PVC/VT通常起源于局部。最可能的机制是延迟后去极化。起源部位的定位基于创建激活图,可结合或不结合起搏标测。特发性PVC/VT最常位于右心室和左心室的流出道,包括主动脉根部。其他典型部位包括三尖瓣或二尖瓣环、乳头肌和浦肯野纤维。对于有症状的单形性PVC/VT,导管消融是抗心律失常药物治疗的替代方法。成功率较高,但标测和消融往往具有挑战性。本文是关于特殊心律失常学和有创电生理学领域特定高级培训系列文章的第五部分。它描述了电生理检查中可获得的病理生理原理、类型和典型发现。