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芬太尼与药物过量:美国巴尔的摩地区阿片类药物使用者对芬太尼风险、药物过量风险行为的认知,以及干预机会

Fentanyl and Drug Overdose: Perceptions of Fentanyl Risk, Overdose Risk Behaviors, and Opportunities for Intervention among People who use Opioids in Baltimore, USA.

机构信息

a Department of Health, Behavior, and Society , Johns Hopkins Bloomberg School of Public Health , Baltimore , Maryland , USA.

出版信息

Subst Use Misuse. 2019;54(6):998-1006. doi: 10.1080/10826084.2018.1555597. Epub 2019 Feb 15.

DOI:10.1080/10826084.2018.1555597
PMID:30767590
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6476669/
Abstract

BACKGROUND

Fentanyl-related mortality has skyrocketed among people who use opioids (PWUO) in North America. The current study of PWUO aims to examine the perceived fentanyl risk and training needs; fatal overdose prevention behaviors; and, feasibility of a peer education approach to reducing fentanyl-related fatal overdoses in Baltimore, Maryland, USA.

METHODS

316 street-recruited PWUO were interviewed about fentanyl in Baltimore, MD.

RESULTS

Most participants (56%) reported that "all" or "almost all" heroin in Baltimore was adulterated with fentanyl and were worried (75%) about their drug buddies overdosing on fentanyl. Half (54%) the participants felt that they needed more training to respond to an overdose. Many participants (66%) reported receiving naloxone or a prescription for it, yet only 17% carried naloxone with them "often" or "always." Among people who inject drugs (PWID) only 13% had naloxone available "often" or "always" when they injected with others, and 51% "often" or "always" injected alone. Almost half of participants (47%) were "very willing" to talk with people in their neighborhood about fentanyl.

CONCLUSIONS

The majority of PWUO perceived that most heroin in Baltimore was adulterated with fentanyl, yet most did not carry naloxone and PWID often did so alone. Given the high perceived risk of fentanyl and relatively low uptake of fatal overdose prevention behaviors, there is an urgency for safe injection facilities, access to medically assisted treatment, and programs that work with the drug-using community to deliver overdose prevention training as well as promote behaviors to carry naloxone and not use drugs alone.

摘要

背景

在北美的阿片类药物使用者(PWUO)中,芬太尼相关死亡率急剧上升。目前这项针对 PWUO 的研究旨在检查对芬太尼的感知风险和培训需求;预防致命过量的行为;以及在美国马里兰州巴尔的摩实施同伴教育方法减少与芬太尼相关的致命过量的可行性。

方法

316 名在街头招募的 PWUO 在巴尔的摩接受了关于芬太尼的采访。

结果

大多数参与者(56%)报告说,巴尔的摩的“所有”或“几乎所有”海洛因都掺有芬太尼,并且担心(75%)他们的毒友会因芬太尼过量而中毒。一半(54%)的参与者认为他们需要更多的培训来应对过量用药。许多参与者(66%)报告说接受过纳洛酮或开了纳洛酮的处方,但只有 17%的人“经常”或“总是”携带纳洛酮。在注射毒品者(PWID)中,只有 13%的人在与他人一起注射时“经常”或“总是”有纳洛酮,51%的人“经常”或“总是”独自注射。近一半的参与者(47%)“非常愿意”与邻里谈论芬太尼。

结论

大多数 PWUO 认为巴尔的摩的大多数海洛因都掺有芬太尼,但大多数人没有携带纳洛酮,而且 PWID 经常独自注射。鉴于芬太尼的高感知风险和相对较低的致命过量预防行为的接受率,迫切需要安全注射设施、获得医疗辅助治疗的机会,以及与吸毒者社区合作开展过量预防培训,并促进携带纳洛酮和不单独使用药物的行为。

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