Stacey Andrew W, Pefkianaki Maria, Ilginis Tomas, Michaelides Michael, Hykin Phill, Webster Andrew, Moore Anthony T, Sagoo Mandeep S
Ophthalmic Surg Lasers Imaging Retina. 2019 Feb 1;50(2):e1-e9. doi: 10.3928/23258160-20190129-12.
To identify the clinical and imaging characteristics of isolated retinal astrocytic hamartomas (IRAH).
A case series of eight patients diagnosed with IRAH.
The average age at diagnosis was 32 years (range: 9 years to 80 years). After a median follow-up time of 59 months, none of the lesions had demonstrated any change or growth. Fundus fluorescein angiogram identified hyperfluorescence in five of six imaged lesions. Fundus autofluorescence (FAF) changes were seen in all eight cases. Ocular ultrasound was able to identify a lesion in only five of the seven cases. Optical coherence tomography (OCT) was able to document the tumor thickness and level of retinal invasion in all cases.
Multimodal imaging is useful for the diagnosis and monitoring of IRAH. OCT and FAF are sensitivity tools for identifying IRA and can be used to follow the thickness and margins of these lesions. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e1-e9.].
确定孤立性视网膜星形细胞瘤（IRAH）的临床和影像学特征。
一系列8例诊断为IRAH的病例。
诊断时的平均年龄为32岁（范围：9岁至80岁）。中位随访时间59个月后，所有病变均未出现任何变化或生长。眼底荧光血管造影显示，6个成像病变中有5个出现高荧光。8例均可见眼底自发荧光（FAF）改变。眼部超声仅在7例中的5例中发现病变。光学相干断层扫描（OCT）能够记录所有病例中肿瘤的厚度和视网膜浸润程度。
多模态成像对IRAH的诊断和监测有用。OCT和FAF是识别IRAH的敏感工具，可用于跟踪这些病变的厚度和边界。[《眼科手术、激光与视网膜成像》。2019；50：e1 - e9。]
