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美国增强恢复和围手术期质量倡议联合共识声明:术前阿片类药物治疗患者的围手术期管理。

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Management of Patients on Preoperative Opioid Therapy.

机构信息

From the Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee.

Department of Surgery, University of Virginia Health System, Charlottesville, Virginia.

出版信息

Anesth Analg. 2019 Aug;129(2):553-566. doi: 10.1213/ANE.0000000000004018.

Abstract

Enhanced recovery pathways have quickly become part of the standard of care for patients undergoing elective surgery, especially in North America and Europe. One of the central tenets of this multidisciplinary approach is the use of multimodal analgesia with opioid-sparing and even opioid-free anesthesia and analgesia. However, the current state is a historically high use of opioids for both appropriate and inappropriate reasons, and patients with chronic opioid use before their surgery represent a common, often difficult-to-manage population for the enhanced recovery providers and health care team at large. Furthermore, limited evidence and few proven successful protocols exist to guide providers caring for these at-risk patients throughout their elective surgical experience. Therefore, the fourth Perioperative Quality Initiative brought together an international team of multidisciplinary experts, including anesthesiologists, nurse anesthetists, surgeons, pain specialists, neurologists, nurses, and other experts with the objective of providing consensus recommendations. Specifically, the goal of this consensus document is to minimize opioid-related complications by providing expert-based consensus recommendations that reflect the strength of the medical evidence regarding: (1) the definition, categorization, and risk stratification of patients receiving opioids before surgery; (2) optimal perioperative treatment strategies for patients receiving preoperative opioids; and (3) optimal discharge and continuity of care management practices for patients receiving opioids preoperatively. The overarching theme of this document is to provide health care providers with guidance to reduce potentially avoidable opioid-related complications including opioid dependence (both physical and behavioral), disability, and death. Enhanced recovery programs attempt to incorporate best practices into pathways of care. By presenting the available evidence for perioperative management of patients on opioids, this consensus panel hopes to encourage further development of pathways specific to this high-risk group to mitigate the often unintentional iatrogenic and untoward effects of opioids and to improve perioperative outcomes.

摘要

加速康复路径已迅速成为择期手术患者标准治疗的一部分,尤其在北美和欧洲。这种多学科方法的核心原则之一是使用多模式镇痛,包括阿片类药物节约甚至无阿片类药物的麻醉和镇痛。然而,目前的情况是出于适当和不适当的原因,阿片类药物的使用处于历史高位,并且在手术前长期使用阿片类药物的患者代表了一个常见且通常难以管理的群体,无论是对加速康复提供者还是整个医疗保健团队来说都是如此。此外,目前仅有有限的证据和少数经过验证的成功方案可以指导护理这些高危患者的提供者在整个择期手术过程中提供治疗。因此,第四次围手术期质量倡议汇集了一个由多学科专家组成的国际团队,包括麻醉师、护士麻醉师、外科医生、疼痛专家、神经科医生、护士和其他专家,旨在提供共识建议。具体而言,这份共识文件的目标是通过提供基于专家意见的共识建议来最小化与阿片类药物相关的并发症,这些建议反映了有关以下方面的医学证据强度:(1)术前接受阿片类药物治疗的患者的定义、分类和风险分层;(2)术前接受阿片类药物治疗的患者的最佳围手术期治疗策略;(3)术前接受阿片类药物治疗的患者的最佳出院和连续性护理管理实践。本文件的主题是为医疗保健提供者提供指导,以减少潜在可避免的与阿片类药物相关的并发症,包括阿片类药物依赖(躯体和行为)、残疾和死亡。加速康复方案试图将最佳实践纳入护理路径。通过呈现围手术期管理阿片类药物患者的现有证据,这个共识小组希望鼓励进一步制定针对这一高危人群的具体方案,以减轻阿片类药物经常带来的无意的医源性和不良影响,并改善围手术期结局。

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